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Department of Pharmaceutical Sciences

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PhD Program for Pharmaceutical Sciences

Around 80 doctoral students at the DPhW conduct research on the discovery, development, manufacture, mode of action, application and safety of medicines as part of their doctoral studies. We see this diversity in research fields as a strength and would like to foster synergies through a structured PhD program.

The "PhD Program for Pharmaceutical Sciences" places a strong focus on the individual research, combined with in-depth technical content and the acquisition of cross-disciplinary competencies.

The goal of the program is to provide optimal preparation both for a career in science and for later employment in hospitals, government agencies or industry.

Here we will give you important information and upcoming events as well as the program details with useful links . If you have any questions, please contact the program coordinator Anima Schäfer .

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Department of Chemistry, Biochemistry and Pharmaceutical Sciences

More than 20 leading scientists lecture and research at our department. We offer a modern curriculum within the Bachelor and Master programs "Chemistry and Molecular Sciences", "Biochemistry and Molecular Life Science" and "Pharmaceutical Sciences". As a further step we offer an attractive and versatile PhD program in Chemistry and Biochemistry. 

Furthermore, there are up to four apprenticeship positions as "Laborantinnen" or "Laboranten EFZ / Fachrichtung Chemie"  to be filled per year at the Department of Chemistry, Biochemistry and Pharmaceutical Sciences.

Please follow the link for an overview of the department:

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The dynamic and vibrant virtual community in Pharmaceutical Sciences and Pharmacy at the University of Bern: www.pharmabern.ch

Material of the Month March 2024

Supramolecular Self-Assembly of Pyrene-DNA Conjugates into Columnar Vesicles

Method of the Month February 2024

A Versatile APT Experiment for Routine 13 C Nuclear Magnetic Resonance Spectroscopy

Molecule of the Month January 2024

Discovery of Antibacterial Manganese Tricarbonyl Complexes

PhD Theses Awards

Congratulations to Aline Carrel, Lukas Gurzeler, Corinne von Känel

Material of the Month December 2023

The Impact of Order and Disorder in the Doping of Semiconducting Polymers

10 million euros for the search for new electrocatalysts

An international group of researchers with participation from the University of Bern is using new concepts to search for efficient and durable electrocatalysts for the energy transition. They are being funded by the European Research Council (ERC) with 10 million euros.

A gel against intestinal inflammation

Researchers at the University of Bern have developed a gel that could be used to treat chronic intestinal inflammation more specifically and with fewer side effects.

Material of the Month November 2023

The More the Better: Formation of Single Phase High Entropy Alloys

Molecule of the Month October 2023

NADH-Type Hydrogen Storage and Release on an Iridium PYE Complex

First Year Graduate Student Symposium 2023

Congratulations to the winners of the "Best Presentation Award": Luca Vedani (Hevia group) Jérémie Reusser (Reymond group) Divyansh Gautam (Arenz group)

Molecule of the Month September 2023

Protein Engineering Allows Efficient Light-Driven ATP Synthesis

Method of the Month August 2023

New Generation of 99m Tc Radionuclide Generators for Radiopharmaceutical Applications

Measurement of the Month July 2023

Sources of Elemental Carbon (EC) in the Atmosphere of Svalbard

Molecule of the Month June 2023

Chromophore-Loaded CRALBP Nanoparticles Restore Rod Function in Chromophore-Deficient Mice

Method of the Month May 2023

Rapid Pesticide Screening by Swab Spray Mass Spectrometry

Molecule of the Month April 2023

Length does matter

Dem Fachkräftemangel in Pharmazie entgegenwirken

Seit 2020 bietet die Universität Bern ein schweizweit einzigartiges, bifakuItäres Vollstudium in Pharmazie an. Der Studiengang betont die Pharmazie als Brücke zwischen Naturwissenschaften und Medizin und trägt dazu bei, den Mangel an Apothekerinnen und Apothekern in der Schweiz zu bekämpfen. Im Herbst 2022 schloss der erste Jahrgang das Pharmazie-Studium erfolgreich ab.

Wertvolle Impulse für die Chancengleichheit

Die Universität Bern vergab dieses Jahr den Chancengleichheitspreis «Prix Lux» an den Nationalen Forschungsschwerpunkt «RNA & Disease» – für neue Ansätze zur Unterstützung junger Mütter und Väter, die der Fortführung ihrer Karriere dienen.

Successful Sinergia Application

The Sinergia Grant Application “Exploring New Building Blocks for Molecular Electronics: Charged and Excited States of Molecules on Surfaces” with PD Dr. Shi-Xia Liu as one of the PIs has been approved by the SNSF. The project will involve a collaboration between EPFL, UniBasel and UniBern (DCBP & IAP).

Molecules of the Month December 2022

Crowd-Sourced Metal Complexes as Antifungals

Welcome to Prof. Dmitry Katayev!

Since October 1st, 2022, he officially is Assistant Professor with Tenure Track in Organic Chemistry at the DCBP.

BRIDGE grant awarded to David Roura Padrosa

The researcher from the DCBP received the BRIDGE Proof of Concept grant for his research in the field of enzyme immobilization.

First Year Graduate Student Symposium 2022

Congratulations to the winners of the "Best Presentation Award": Kovida Sharma (Šolomek group) David Anderson (Hevia group) Alain Rieder (Broekmann group)

Creation of a detailed "catalogue" of degradation products in cells

Cells have their own quality control to prevent the production and accumulation of harmful proteins. This quality control is essential for correct embryonic development in all mammals and plays an important role in tumors and genetic diseases such as cystic fibrosis. A group of researchers from the University of Bern and the University of Basel have now made visible and cataloged for the first time, "blueprints" that give rise to defective proteins and are normally recognized and rapidly degraded in cells. This leads to a better understanding of this degradation mechanism and helps in the development of new therapeutic approaches.

Presentation at the MINT-Day 2021 of the University of Bern

Virusinvasion durch die Atemwege © 2021 Minela Colakovic (Gruppe von PD Dr. Carlos Ros)

Vom DNA-Plasmid zum Protein © 2021 Christoph von Ballmoos

Einführung in ein elektrochemisches Labor © 2021 Aline Bornet & Gustav Wiberg (Gruppe von Prof. Matthias Arenz)

Award for Prof. Dr. Eva Hevia

Prof. Dr. Eva Hevia has been awarded with the "RSEQ Research Excellence Award 2021"

Kagome graphene promises exciting properties

For the first time, physicists from the University of Basel, working in collaboration with the Department of Chemistry, Biochemistry and Pharmaceutical Sciences of the University of Bern, have produced a graphene compound consisting of carbon atoms and a small number of nitrogen atoms in a regular grid of hexagons and triangles. This honeycomb-structured “kagome lattice” behaves as a semiconductor and may also have unusual electrical properties. In the future, it could potentially be used in electronic sensors or quantum computers.

SRF-Sendung «Kopf voran»

Podcast-Folge über Gertrud Woker, die erste Schweizerin, welche in Chemie doktoriert hat

Podcast-Folge mit den Gedanken von sechs Studierenden zum Frauenanteil an der Universität Bern und anderen Themen

Von den Löchern im Periodensystem

Vor 150 Jahren, im März 1869, erfand Dmitri Mendelejew das Periodensystem der Elemente. Im Gespräch mit dem emeritierten Chemie-Professor Heinz Gäggeler hat «uniaktuell» allerhand Interessantes über die Elemente von 1 Wasserstoff bis 118 Oganesson erfahren.

The chemist and her «big beast»

Follow Clémence Delalande and discover how a day of a chemistry researcher looks like.

Award for Prof. Dr. Hans Ulrich Güdel

Prof. Dr. Hans Ulrich Güdel has been awarded with the "ICL 2017 Prize for Luminescence Research"

For Nostalgists: Link to the Old DCB Website

"Früher war alles anders - und einiges war besser ..." The old DCB website will no longer be updated, however!

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14 th Swiss Course on Medicinal Chemistry 2022 Leysin Switzerland

• Special Event: Les Mosses (Tue, Oct 11, 2022)
• Special Event: Journey to the heart of the vineyards (Wed, Oct 12, 2022)
• Special Event: Dinner "La Fromagerie" (Thu, Oct 13, 2022)
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14th Swiss Coursee on Medicinal Chemistry 2022

This five-day Medicinal Chemistry School that was organized by the Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society  focused on most modern aspects associated with small molecule drug discovery, highlighting the methodologies and technologies supporting hit generation, lead finding and lead optimization campaigns.

In the beautiful and scenic village of Leysin , close to Lake Geneva, more than 100 young scientists met with app. 35 international renowned expert speakers and instructors.

As in previous years, the teaching content was targeted at young scientists working in the area of medicinal chemistry , but also from flanking disciplines such as biochemistry , pharmacy , pharmacology , or biophysics from the pharmaceutical and biotech industry. Given the broad spectrum and the timeliness of scientific topics discussed, the course also provided a valuable opportunity for advanced medicinal chemists to get acquainted with most recent developments in e.g. the medicinal chemistry of novel target families, novel compound classes, and most modern optimization paradigms. In addition, a number of PhD students and postdocs were able to attend to receive a broad overview on scientific disciplines involved in modern drug discovery.

The event was thematically structured along key topics of strategic relevance for medicinal chemistry that will be presented by opinion leaders in the field. The teaching content was further intensified by hands-on tutorials in which the theoretical learning’s can immediately be applied to real life problems of pre-clinical drug discovery.

Co-chairmen

Dr. Gerhard Müller, Anavo Therapeutics

Prof. Dr. Beat Ernst, University of Basel

Dr. Katarzyna Borsuk, ZoBio

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Swiss Chemical Society CHIMIA DMCCB Former SCMC Editions

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Meeting Chair

Dr. Gerhard Müller, Anavo Therapeutics Prof. Dr. Beat Ernst, University of Basel

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Pharmaceutical Chemistry

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Graduate School of Chemical and Molecular Sciences Zurich

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to the Graduate School of Chemical and Molecular Sciences Zurich.

The Graduate School of Chemical and Molecular Sciences Zurich (CMSZH) is a melting pot of science and innovation, offering a highly competitive Ph.D. program for a comprehensive and challenging education.

Highly motivated and outstanding young researchers from all over the world are invited to join. The Graduate School of Chemistry and Molecular Sciences Zurich offers great working conditions for talented young researchers under the supervision of world renowned scientists.

Applications:   >> learn more

Weiterführende Informationen

Prof. Dr. Felix Zelder

Head of CMSZH

University of Zurich Department of Chemistry Winterthurerstrasse 190 CH-8057 Zürich

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11 medicinal-chemistry-phd positions in Switzerland

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PhD Position: Nanotechnology for Gas Sensing

100%, Zurich, fixed-term The research of the Human-​centered Sensing Laboratory centers around physics, chemistry and medicine to gain new fundamental understanding in micro/nanosystems

Principal Scientist - Medicinal Chemist (80-100%*)

What you will bring to the role: • A PhD in chemistry or related life science discipline with excellent theoretical and practical experience in e.g. synthetic organic chemistry , drug discovery

Biozentrum PhD Fellowships – Summer Call 2024

19 Mar 2024 Job Information Organisation/Company University of Basel Research Field Biological sciences » Biology Biological sciences » Other Chemistry » Biochemistry Medical sciences » Other

Ph.D. Position at the Department of Biomedical Engineering

28 Feb 2024 Job Information Organisation/Company University of Basel Research Field Engineering » Biomedical engineering Technology » Biotechnology Engineering » Materials engineering Chemistry

PhD position in Molecular Pharmacology

7 Feb 2024 Job Information Organisation/Company ETH Zürich Research Field Chemistry » Biochemistry Medical sciences » Medicine Biological sciences » Other Medical sciences » Other Pharmacological

Postdoctoral position for research in functional materials for sensing technology in e-textiles

17 Feb 2024 Job Information Organisation/Company ETH Zürich Research Field Chemistry » Analytical chemistry Engineering » Materials engineering Technology » Nanotechnology Chemistry » Other

information on our research activities can be found here . The PhD position encompasses research work, and presentation of scientific data in frame of group meetings and at international conferences. In

7 Feb 2024 Job Information Organisation/Company University of Basel Research Field Engineering » Biomedical engineering Technology » Biotechnology Chemistry » Other Researcher Profile First Stage

in applying your fundamental knowledge in, but not limited to, materials science, synthesis, analytical chemistry , electrochemistry, and chemical engineering towards producing relevant and impactful

PhD in Electrochemical and materials engineering for nerve regeneration

100%, Zurich, fixed-term Are you passionate about pushing the boundaries of biomedical and electrochemical engineering? The Lukatskaya and Herrmann Laboratories are seeking a highly motivated PhD

Searches related to medicinal chemistry phd

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Pharmaceutical Biology

Main content, total synthesis and medicinal chemistry of natural products.

Our research is centered on the chemical synthesis of bioactive natural products/natural product analogs and their biological characterization. Major objectives of our work are (i) the total synthesis of bioactive natural products and their profiling; (ii) the elucidation of the structural requirements for biological activity; (iii) the assessment of opportunities for structural simplification and molecular editing of complex natural products; and (iv) in selected cases, mechanism of action and structural studies. Ultimately, all of these efforts aim at the identification of new leads for drug discovery or potential drug candidates, with a main focus on cancer and infectious diseases. The work in the group is largely chemistry-based, while biological questions are addressed in collaborations with appropriate partners.

Research news

Our most recent paper describes much of our synthetic work on 3-deoxy-12,13- trans -epothilone A analogs and the investigation of their biological activity. This work has revealed some surprising insights into the chemistry of these systems as well as the structural requirements for biological activity. The work is published online in Helv. Chim. Acta as an Accepted Paper: Download http://dx.doi.org/10.1002/hlca.201900078 vertical_align_bottom

The main teaching responsibilities of the professorship are (1) in the education of pharmacy students in pharmaceutical biology; and (2) the education of medical students in basic general and organic chemistry. The teaching in pharmaceutical biology covers basic aspects of the structure and biosynthesis of plant constituents and the pharmacological effects and therapeutic applications of biogenic drugs of plant origin (extract-based herbal medicines; isolated natural products). At the practical level it includes the microscopic analysis of plant material (pharmacopoeia), the chromatographic analysis of medicinal plants, extraction methods, qualitative/quantitative determination of medicinal plant constituents, and the isolation of natural products. The teaching for medical students addresses the most important fundamental concepts in chemistry (atomic structure, chemical bonds, thermodynamics and kinetics of chemical reactions, acid-base equilibria, types and reactivity of organic compounds, stereochemistry, biomolecules) and highlights connections between chemical processes and medically important biochemical, physiological, and pharmacological questions. In addition, we are also involved in Master level courses on medicinal chemistry and drug discovery. For more information please consult the course catalog of the ETH Zürich.

Roche Internships in Medicinal CHemistry (RiCH)

The Roche Internship in Medicinal Chemistry (RiCH) Programme invites chemistry students to become an integral part of one of our Medicinal Chemistry laboratories in Basel, Switzerland for six months/one year. Medicinal Chemistry is at the heart of the drug discovery process and the successful applicant will synthesise novel molecules for innovative biological targets at one of the world’s leading pharmaceutical companies.

Who: passionate & motivated chemistry student who in the 2020-2021 academic year will be in the penultimate or last year of study, at the “year in industry” junction of their studies or in a gap year before starting a phd, what: be part of a research laboratory and research team involved in lead generation and/or lead optimisation projects synthesising novel molecules for innovative biological targets, duration: 6-12 months, location: roche innovation center basel, switzerland, career benefits: gain experience in the use of modern organic chemistry synthetic methods and purification technologies through hands-on experience and a dedicated tutorial programme; receive complementary education with an especially tailored tuition program through which you will deepen your understanding in organic and medicinal chemistry and improve your presentation skills, financial support: monthly internship salary, travel expenses, accommodation in a shared house and reimbursed costs for swiss work permit application, academic support: candidates must provide one academically relevant letter of support upon application, how to apply, all positions will be posted on the roche careers website until october 7th (12pm). you can apply here . learn more about roche pharma research and early development (pred) here ., first 100 days at roche , it’s hard to believe i have been at roche for over 100 days. from the first nervous tour of my lab at the beginning of september to now, my confidence as a medicinal chemist and as a person has grown monumentally. i have developed my practical skills in and outside the lab, and the rich tuition has improved both my presenting and problem-solving skills. being part of this programme is such a privilege. i learn so many new things every day, not just from my supervisor, who has played a massive role in my amazing experience so far, but from the whole medchem community. what i have particularly enjoyed is the multidisciplinary project team and gaining an understanding of not only the chemistry, but also the biology and especially the molecular modelling for structure-based discovery and how all these elements combine to move a project forward. i am so excited for what the next eight months have in store., briana norris, university of edinburgh, scotland, since joining roche, i have been fully immersed in a culture where everyone is passionate about delivering ground-breaking results. surrounded by enthusiastic individuals, we are always encouraged to push ourselves further along the steep learning-curve that promotes confidence and proficiency when working in a lab. the extensively equipped labs offer the chance for young chemists to be engrossed in the fast-paced nature of the pharmaceutical industry and, for me, have heightened the desire to continue a career path within this field., aside from chemistry, the rich tuition programme takes a deep interest in personal development, particularly focusing on communication skills through presentations, which stands us in good stead for the future, regardless of our career path. the other interns, colleagues and the company as a whole are always doing their bit to make this internship exciting and enjoyable. samuel foster, university of york, uk, it seems so long ago, yet at the same time like it was yesterday that i first walked into building 1 along with 14 other people i had met only hours before.  since then i have made lifelong friends and grown in confidence both as a person and in my ability as a chemist. i have learnt so much from working in a lab on a daily basis, attending group project meetings and the valuable tuition sessions where i have been able to improve my presentation skills. i am really looking forward to the next 100 days ellie stammers, university of york, uk, my first hundred days at roche have gone by way too quickly in this fast-paced and dynamic setting. i was amazed by the inclusive environment at roche and the extent of encouragement from my group to implement my own ideas, suggestions and initiatives. everyone is very polite and friendly and people always seem to carry a warm-hearted grüezi for you in their pockets. it has been a great opportunity for me to take advantage of the interdepartmental collaboration, witness in vivo tests and learn first-hand from experts in analytics and bio-catalysis teams at roche. the weekly student seminars have allowed me to hone my communication skills while simultaneously challenging and improving my knowledge of synthetic organic chemistry. but the internship is more than just chemistry. i have spent my weekends searching for the best glühwein (mulled wine) in germany, snowboarding off-piste in the alps and trying new foods, sports and dances, all while meeting incredible new people. in my opinion, the rich internship offers endless possibilities and great potential for personal growth and i can’t wait for what the coming months will bring., miroslav kosar, university of edinburgh, scotland, in my first 100 days i gained an insight into roche’s approach to face the world’s most crucial challenges in creating new treatments for patients in need. as a student, i am a part of the small molecule research community and i work hand in hand with scientists in my project. potential drugs in the form of novel molecules are designed, synthesised and evaluated on the daily basis. research is carried out at a fast pace and new knowledge is created very rapidly. the programme gives me the opportunity to extend my theoretical and practical strengths in organic chemistry and hone my presentation skills by giving talks almost every week. i see the knowhow i have gained in the last 100 days as exceptional preparation for a future phd programme. the internship in medicinal chemistry at roche is more than just an industrial placement. it’s an opportunity to work with remarkable people and grow and learn every day., kenneth atz, university of basel, switzerland, looking back on my first one hundred days at roche, i can safely say that i am delighted with the whole experience. ever since i started, there has been an exceptionally steep learning curve. however, this is not forced on you; you set your own pace and how much you want to learn. there is always plenty to do and learn for those who are willing and seek out knowledge, in my experience, people have adapted how they approach me as i have developed. at the start, everyone taught me as much as they could and were extremely supportive, but as i became more confident, independent and had ideas of my own, their stance towards me has been no different to any other employee. , the people in the medicinal chemistry department are truly outstanding synthetic and medicinal chemists and many come from elite research groups in academia. so the fact that lab heads (or anyone you can get a hold of, for that matter) are always happy and willing to share their knowledge on biology, biological data and (most importantly) chemistry is an amazing opportunity, as an undergraduate, this is the year i feel like i'm really starting to become a chemist. the vast amount of practical work has helped me become confident in my abilities in the lab. the tuition programme complements this perfectly with a theoretical approach and building soft skills such as presenting., from getting to know the other people on the rich program, it is evident that the recruitment process is heavily focused on character as well as knowledge – and rightly so. as a result, the atmosphere with the other interns is awesome all in all, we are a diverse but compatible set of people and we have a great time together. michael bogdos, university of strathclyde, glasgow, scotland, after my first hundred days at roche, i feel that this outstanding experience added a lot of value to my chemistry education. first of all, with the help of my supervisor my ability to work proficiently and independently in the lab has improved a lot since the beginning., the part i found most interesting – along with the teamwork and cooperation between people – is the chance to tackle a wide spectrum of different chemical reactions: from well-established chemistry to the recent breakthrough in synthesis, everyday life in roche's pred laboratories is never boring; it’s challenging but fulfilling, too., so far i have really enjoyed the opportunity that roche gave me and i am sure the rest of the internship will be even more rewarding for me, both as a chemist and from a personal perspective., peter belotti, university of regensburg, germany, my first 100 days at roche have been exciting, challenging yet extremely valuable. to have the opportunity to work in a leading, global company with such a friendly environment and welcoming culture is incredible. the rich programme has boosted my confidence as a chemist, honed my practical skills through working in the lab and improved my chemical knowledge through the tuition. i have found working on an exciting project in a talented and supportive lab team very rewarding. as well as synthesising and developing novel compounds, you get to learn and understand the biological and the medicinal applications of your compounds. overall, my first 100 days have been very enjoyable and i would recommend anyone take up this fantastic opportunity. , nicole tsang, university of nottingham, uk, accepting this industrial placement was one of the smartest choices i’ve made. from the very beginning, the other students and i received a thoughtful, fantastic welcome. every day i wake up motivated to progress and learn more. i feel fulfilled in this multicultural, cross-functional environment, where i can evolve and improve all the time. working at roche allows me to constantly improve my skills. i analyse biological data and design new compounds in order to explore the structure-activity relationship. in addition, i find the quickest synthesis route, then carry out the synthesis, purification and analytics to confirm the structure and purity of the bio-active molecules. i regularly present my project and explain organic chemistry during meetings or with the rich special tuition programme in front of both experienced chemists and my peers., i am looking forward to the next few months of this marvellous journey. i can only recommend this internship: not only is it a tremendous work experience, you will also meet many wonderful people and find a new family amongst the other students., vincent porte, university of montpellier, france, my first 100 days here at roche have been truly exhilarating., it is such a rewarding experience to be working alongside such experienced scientists who are supportive in my learning and development and ever-willing to share their expertise. thanks to the collaborative work environment, my confidence and proficiency in the labs have massively improved., presentation of ideas and clarity of sharing information had never been my strong point, but the rich tutoring program has provided a well-rounded development, as we are regularly given the opportunity to stand up and present our work in front of fellow students. also hearing about other people’s experiences in their projects inspires me to try out new things., my time here is proving to be invaluable in shaping my future career path as a chemist. moreover, basel is also a great city to be living in and there are so many opportunities to live life to the full and embrace new cultures as an international student in switzerland. i am so grateful to be in this position., jennifer carter, university of bristol, uk.

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Postdoc Position in Biological and Medicinal Chemistry at ETH Zurich, Switzerland

Postdoc Position in Biological and Medicinal Chemistry: Join the ETH Laboratory of Toxicology at ETH Zurich, led by Professor Shana Sturla. We are a multidisciplinary team at the chemistry-biology interface, exploring the relationship between chemical structures, biomolecular processes, and cellular responses relevant to chemical safety and drug development. We have a postdoctoral opportunity focusing on chemical biology/medicinal chemistry of nucleic acid-protein interactions. The research includes small molecule synthesis, modified oligonucleotides, protein interactions related to DNA repair in cancer cells, covalent inhibition, and the development of precision cancer therapeutics. High throughput drug screens and in vitro toxicity evaluation may be part of the research. Join us in advancing biological and medicinal chemistry.

Designation: Postdoctoral Researcher

Research Area: Biological and Medicinal Chemistry

Location: ETH Zurich, Department of Health Science & Technology, Switzerland

Eligibility/Qualification:

• PhD or equivalent in chemistry, medicinal chemistry, or a related discipline .
• Proficiency in organic synthesis of small molecules.
• Excellent written and oral communication skills in English.
• Independent, flexible, and motivated to work in an international and team-oriented environment.

Job Description:

Postdoc Position in Biological and Medicinal Chemistry

As a Postdoc in Biological and Medicinal Chemistry, your research will involve:

• Synthesis of small molecules and modified oligonucleotides.
• Evaluation of interactions with proteins related to DNA repair in cancer cells.
• Covalent inhibition studies.
• Contribution to the development of precision cancer therapeutics.
• Possible involvement in high throughput drug screens and in vitro toxicity evaluations.
• Collaborative research opportunities in environmental toxicants, DNA damage, mutagenesis, and microbial metabolism of chemicals.

The initial contract is for 1 year, with the possibility of extension up to 6 years, depending on funding availability.

How to Apply: Interested candidates should send the following to [email protected] :

• A brief email describing research experience and scientific/professional goals.
• CV including publication list and contact information for 3 referees (do not include letters of recommendation).

Applications will be considered on an ongoing basis until the position is filled.

For inquiries, contact Prof. Shana Sturla at [email protected] .

Last Date for Apply: Applications accepted until the position is filled.

Salary: Salary details available upon inquiry. Join ETH Zurich, a world-leading university in science and technology, and contribute to groundbreaking research in biological and medicinal chemistry.

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Research Associate at IIT Delhi, New Delhi, India: Apply by 15...

Research update: 23 april 2024- career options with researchersjob.

The PhD Program in Medicinal Chemistry educates and trains students in the design and synthesis of novel, biologically active compounds and in delineating their mechanisms of action using biochemical, biophysical, and pharmacological approaches. Research specializations are available in synthetic, biochemical/pharmacological, and biophysical aspects of medicinal chemistry. Doctoral research in these specializations will relate to faculty areas of research, which currently include substance use disorders and addiction; neuropathic pain; obesity and metabolic disorders; neuropsychiatric disorders (psychoses, ADHD, depression, anxiety, eating disorders); and neurodegenerative diseases.

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Groundbreaking Cancer Gene Therapy

This specialization offered by the Center for Drug Discovery (CDD) trains students in the design and synthesis of novel biologically active compounds and in the study of their mechanisms of action using biochemical, biophysical, and pharmacological approaches. Concentrations are available in synthetic, biochemical/pharmacological, and biophysical medicinal chemistry. The CDD’s excellence in teaching has been recognized by the award of a training grant from the National Institute on Drug Abuse for predoctoral and postdoctoral training in development of medications. These will be targeted to treat drug abuse; addiction; and other indications such as neuropathic pain, obesity, neuropsychiatric disorders (psychoses, ADHD, depression, anxiety, eating disorders); and neurodegenerative disorders.

Where They Work

• Novartis Institutes for Biomedical Research

What They Do

• Healthcare Services
• Business Development

What They’re Skilled At

• High-Performance Liquid Chromatography
• Pharmaceutical Industry
• Cell Culture
• Biotechnology

Application Materials

Application.

• Application fee – US $50
• Three letters of recommendation
• Transcripts from all institutions attended
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MedChem Banner

TOP RESEARCH EXPENDITURE IN THE U.S.

Medicinal chemistry involves the application of a number of specialized disciplinary approaches all focused on the ultimate goal of drug discovery.  Drug target identification and validation, rational (target-based) drug design, structural biology, computational-based drug design, methods development (chemical, biochemical, and computational), and “Hit-to-lead” development are all aspects of medicinal chemistry.  The techniques and approaches of chemical biology, synthetic organic chemistry, combinatorial (bio)chemistry, mechanistic enzymology, computational chemistry, chemical genomics, and high-throughput screening are all used applied by medicinal chemists towards drug discovery.

For our Pharm.D. students, medicinal chemistry is integrated with pharmacology to present a coherent picture of the principles of drug action.  Pharmacology mainly deals with drug action at the cellular, tissue/organ and organism levels.  Medicinal chemistry focuses on the molecular aspects of drug action: interactions with the drug targets from both the drug and the target point of view, the relationship of drug chemical structure to drug action and the effects of metabolism on the drug structure and hence its action.

In 1913, the University of Michigan first outlined a graduate program offering M.A., M.S., Ph.D. and D.Sc. degrees in a joint effort between the Graduate Department (now the Horace H. Rackham School of Graduate Studies) and the Pharmacy Department (now College of Pharmacy).  As a discipline, Medicinal Chemistry in the United States started with the appointment of Dr. F. F. Blicke as Assistant Professor of Pharmaceutical Chemistry in 1926.  Prof. Blicke initiated the first graduate education program in Pharmaceutical Chemistry, focusing on synthetic organic chemistry.  The program expanded in the 1950s to include analytical aspects and pharmaceutics.  After Prof. Blicke’s retirement in 1960, his former student, Prof. J. H. Burkhalter returned to the College and argued for an independent graduate education program in Medicinal Chemistry.  Along with the support of Graduate School Dean Alfred Sussman and the participation of a core group of interdepartmental faculty (within and outside of the College of Pharmacy), in 1967 Prof. Burkhalter established the Interdepartmental Program in Medicinal Chemistry (Med Chem IDP).  The Med Chem IDP was established to train students in a broad range of chemically-based disciplines so that its graduates are able to apply the rigor and methods of the physical sciences to drug discovery research.  Subsequently, in 1973 Prof. Raymond Counsell and in 1977 Prof. Leroy B. Townsend were appointed as Director of the Med Chem IDP.  The Med Chem IDP is administered by the Horace H. Rackham School of Graduate Studies with direct oversight by the College of Pharmacy.

In 1999, in response to the significant growth of the College of Pharmacy under previous Dean Ara G. Paul, then Dean George L. Kenyon initiated a process of departmentalization of the College of Pharmacy.  Prof. James K. Coward was the first Chair of the Department of Medicinal Chemistry and Director of the Med Chem IDP.  The Department of Medicinal Chemistry is the administrative component of the College of Pharmacy that oversees the Medicinal Chemistry faculty, research scientists and postdoctoral fellows (e.g., recruitment, mentoring, evaluation), has responsibility for the medicinal chemistry Pharm.D. and Ph.D. courses and seminar program, and coordinates the participation of medicinal chemistry faculty in College-level committees and other administrative duties.

The Department of Medicinal Chemistry is the home for the Med Chem IDP Ph.D. program, which serves to administer the Med Chem Ph.D. program, with responsibility for graduate student recruitment, training/mentoring, progression and graduation.  The Med Chem IDP includes all faculty from the Department of Medicinal Chemistry as well as select faculty from the Department of Pharmaceutical Sciences in the College of Pharmacy and a variety of schools (e.g., Literature, Science and the Arts, Medical School) and departments at Michigan (e.g., Biological Chemistry, Biophysics, Chemistry, Pathology, Pharmacology, Radiology).  Approximately half of the Med Chem IDP faculty have their primary appointments outside of the Department of Medicinal Chemistry.  These faculty currently mentor ~20% of the Med Chem Ph.D. students and are fully engaged in the Med Chem Ph.D. program in many other ways including seminar attendance, recruitment of students, teaching in our graduate courses, and serving on candidacy and dissertation committees.  There is an annual meeting of the Med Chem IDP faculty to review the status of the IDP and the students.

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Department of Chemistry and Applied Biosciences

Faculty loc.

Prof. Dr. Jeffrey W. Bode Synthesis & Chemical Biology Group Website

Prof. Dr. Erick M. Carreira Organic Synthesis, Natural Products Group Website

Prof. Dr. Peter Chen Reaction Mechanisms Group Website

Prof. Dr. Kathrin Lang Head of LOC Chemical Biology & Synthetic Biochemistry Group Website

Prof. Dr. Bill Morandi Homogeneous Catalysis and Synthesis Group Website

Prof. Dr. Helma Wennemers Organic Chemistry & Chemical Biology Group Website

Prof. Dr. Renato Zenobi Analytical Chemistry Group Website

Adjunct Professors  

Prof. Dr. Peter A. Kast Function & Evolution of Biocatalysts Group Website

Prof. Dr. Carlo Thilgen Nanostructural Surfaces

Permanent Scientists and Independent Investigators  

Dr. Marc-Olivier Ebert Structure and Dynamics by NMR Website of NMR Service

Dr. Stamatios Giannoukos Chemical analysis of exhaled breath applied to questions concerning nutrition

Dr. Naresh Kumar Nanoscale chemical analysis, spectroscopy, and imaging

Dr. Bartosz Lewandowski Designing synthetic supramolecular assemblies that mimic the functions of biological systems and machines

Dr. Josep Mas-Roselló Catalyst design, asymmetric synthesis, sustainable chemistry external page Group Website call_made

Dr. Vijaya Raghavan Pattabiraman Peptide Structures and Synthetic Modified Proteins

Dr. Alexandra Tsybizova Reaction Mechanisms in the Gas Phase

Dr. Susanne Wolfrum Chemical Biology, Biology of Metabolic Disease