1. Oncology: Colorectal Cancer

    research paper on colon cancer

  2. Case Study for Colon Cancer

    research paper on colon cancer

  3. (PDF) Colorectal cancer: a review

    research paper on colon cancer

  4. (PDF) Cell type-specific response of colon cancer tumor cell lines to

    research paper on colon cancer

  5. (PDF) The effect of probiotics on colon cancer development

    research paper on colon cancer

  6. Lung and Colon Cancer Histopathological Image Dataset (LC25000

    research paper on colon cancer


  1. Colon cancer on the rise in young Americans, study says

  2. 2024 Colon Cancer Screening Guidelines Explained #coloncancerawareness

  3. Colon cancer research looks at starting point

  4. What is Research


  1. Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies

    1. Introduction. Colorectal cancer (CRC), which comprises colon and/or rectum cancer, represents a significant health problem as the world's third most commonly diagnosed and second most fatal cancer globally [].Approximately 9.4% of cancer-related deaths were due to CRC in 2020 [].However, in light of the significant increase in the number of identified cases in the older population, it is ...

  2. A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors

    Colorectal cancer (CRC) is third in terms of recognition (6.1%) and second in terms of mortality (9.2%). It is estimated that by the year 2035, the total number of deaths from rectal and colon cancer will increase by 60% and 71.5%, respectively . These figures may differ from country to country depending on the degree of economic development.

  3. Colorectal Cancer Screening

    Colorectal cancer is one of the most common cancers worldwide. 1 In the United States, 147,000 individuals received a diagnosis of the disease in 2020, and 53,200 died from it. 2 Most patients with colorectal cancer are older than 50 years of age at diagnosis. 2 Men have a higher risk than do women and are on average 5 to 10 years younger than women when they receive the diagnosis. 3,4

  4. Colorectal cancer

    Colorectal cancer, also known as bowel cancer, is a cancer formed by uncontrolled cell growth in the colon or rectum (parts of the large intestine), or in the appendix. Genetic analysis shows that ...

  5. Effect of Colonoscopy Screening on Risks of Colorectal Cancer and

    Supported by research grants from the Research Council of Norway (197309), Nordic Cancer Union, Norwegian Cancer Society, and Health Fund of South-East Norway (5135); bowel preparation free of ...

  6. Colon cancer

    Colon cancer is the disease characterized by the development of malignant cells in the lining or epithelium of the first and longest portion of the large intestine. Latest Research and Reviews

  7. Colorectal Cancer Research Articles

    Researchers have identified four warning signs that they believe may help identify colorectal cancer early in younger adults. The signs or symptoms are abdominal pain, rectal bleeding, diarrhea, and iron deficiency anemia. Drug Regimen Boosts Survival of People with Advanced Colorectal Cancer. Posted: May 24, 2023.

  8. Recent Advances in the Treatment of Colorectal Cancer: A Review

    Abstract. Colorectal cancer (CRC) is the third most common cancer worldwide, and surgical treatment remains the first-line treatment to provide a cure. In addition to the aging population, obesity, low physical activity, and smoking habits increase CRC risk. Despite advances in surgical techniques, chemotherapy, and radiotherapy, colorectal ...

  9. PDF Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology

    Colorectal cancer (CRC), which comprises colon and/or rectum cancer, represents a significant health problem as the world's third most commonly diagnosed and second most fatal cancer globally [1]. Approximately 9.4% of cancer-related deaths were due to CRC in 2020 [2]. However, in light of the significant increase in the number of ...

  10. Colorectal cancer statistics, 2023

    However, the sex disparity varies by age at diagnosis and tumor location. For example, the male-to-female incidence RR ranges from 1.10 (95% CI, 1.09-1.11) for proximal colon cancer to 1.61 (95% CI, 1.60-1.63) for rectal cancer, as reflected in the relatively large differences in tumor distribution (Table 2).

  11. Colon Cancer

    Colon cancer screening is recommended and may be performed using various modalities.Screening initiation and follow-up guidelines vary among organizations. Colon cancer diagnosis requires a tissue biopsy, usually obtained via colonoscopy. All newly diagnosed colon cancers should be screened for common genetic mutations, and a complete ...

  12. Colon Cancer

    Colon Cancer and Right-Sided Colon Cancer on Computed Tomography). Ultimately, a colonoscopy is required for a tissue diagnosis. ... Systemic therapy for colon and rectal cancers is addressed jointly by clinical research and practice. In the 1990s, 5-FU/LV monotherapy was the standard first-line therapy, with an approximate mOS of 12 months. ...

  13. The effect of time before diagnosis and treatment on colorectal cancer

    One hundred and thirty papers were included in the systematic review, eight were included in the meta-analysis. ... in time to diagnosis and treatment in colorectal cancer research. Cancer ...

  14. Advances in Colorectal Cancer Research

    Advances in Colorectal Cancer Research. Colorectal cells grown into organoids, stem cell-derived human 'mini-organs' that are used to study human development and disease. NCI-funded researchers are working to advance our understanding of how to prevent, detect, and treat colorectal cancer. They are also looking at what factors influence ...

  15. Age-related differences in colon and rectal cancer survival by stage

    1. Introduction. In the United States (US), an estimated 150,000 new colon and rectal cancers were diagnosed and over 50,000 deaths occurred in 2021 [1].Over 30 % of colorectal cancers are diagnosed in persons aged 75 and older [2].The 5-year relative survival for colon and rectal cancer is estimated to be 64 % in the US, similar to that in other high-income countries [3].

  16. (PDF) Colorectal cancer: a review

    Colorectal cancer (CCR) is the third most common cancer worldwide in men and women, the seco nd largest cause of. death related to cancer, and the main cause of death in gastrointestinal cancer ...

  17. Imaging in the era of risk-adapted treatment in colon cancer

    New developments in colon cancer. Worldwide, 576 858 patients died from colon cancer in 2020. 1 Interestingly, unlike in rectal cancer, the overall survival of colon cancer patients did not improve in the last decade. 2 In rectal cancer, the use of MRI and different neoadjuvant treatment strategies was quickly adopted and refined. At the same time, the traditional use of computed tomography ...


    In 2012, 614,000 women (9.2% of all new cancer cases) and 746,000 men (10.0% of new cancer cases) were diagnosed with colorectal cancer worldwide 10. Combined, in both sexes, colorectal cancer is the third-most common cancer and accounts for 9.7% of all cancers excluding non-melanoma skin cancer. More than half of the cases occur in more ...

  19. Role of Diet in Colorectal Cancer Incidence

    World Cancer Research Fund/American Institute for Cancer Research. Diet, nutrition, physical activity and colorectal cancer. Accessed September 13, 2020. ... Colon cancer and dietary fat, phosphate, and calcium: a hypothesis.  J Natl Cancer Inst. 1984;72(6):1323-1325.PubMed Google Scholar. 67. Norat T, Riboli E. Dairy products and ...

  20. Laparoscopic surgery for the treatment of colon cancer: the new

    Objective: Colon cancer is a major health problem worldwide with an overall 5-year survival rate of < 50%. Despite advances in the field of oncology proving that adjuvant chemotherapy may improve the outcome, the only treatment with curative intent is represented by surgical resection of the tumor. ... Our goal with this paper was to conduct a ...

  21. Spatially Segregated Macrophage Populations Predict Distinct Outcomes

    Abstract. Tumor-associated macrophages are transcriptionally heterogeneous, but the spatial distribution and cell interactions that shape macrophage tissue roles remain poorly characterized. Here, we spatially resolve five distinct human macrophage populations in normal and malignant human breast and colon tissue and reveal their cellular associations. This spatial map reveals that distinct ...

  22. Cancers

    This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity ...

  23. Earlier Colorectal Cancer Screening in Canada

    This economic evaluation computational study uses microsimulation modeling to estimate the association of a lowered initiation age for colorectal cancer screening by biennial fecal immunochemical test with colorectal cancer incidence, mortality, and health care system costs in Canada.

  24. Colorectal Carcinoma: A General Overview and Future Perspectives in

    Abstract. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with ...

  25. Contribution of pks+ E. coli mutations to colorectal ...

    The dominant mutational signature in colorectal cancer genomes is C > T deamination (COSMIC Signature 1) and, in a small subgroup, mismatch repair signature (COSMIC signatures 6 and 44).

  26. COVID-19 Pandemic's Enduring Imprint on Colorectal Cancer Surgery

    Operations for rectal cancer decreased by 21% and 16% for colon cancer, corresponding to an overall 17.3% decrease in colorectal cancer operations during the first year of the pandemic. Patients in the COVID group had a significantly lower rate of early-stage cancer (35.5% vs. 38.2%) and a significantly higher rate of advanced tumors (19.2% vs ...

  27. (PDF) Colorectal Cancer: A Review of Carcinogenesis, Global

    Among CRC, colon cancer was predominant and accounted for 59.5% of new cases, 61.9% of deaths and rectum cancer had 37.9% of incidence and 36.3% mortality for both sexes and all ages (Figure 5 ).

  28. Bowel cancer is on the rise. Here's how immunotherapy drugs ...

    Bowel cancer is the second-leading cause of cancer deaths worldwide, killing nearly 1 million people per year, and cases of colorectal cancer have been on the rise. But there are glimmers of hope ...

  29. Research status and potential applications of circRNAs affecting

    DOI: 10.1016/j.lfs.2024.122870 Corpus ID: 270785370; Research status and potential applications of circRNAs affecting colorectal cancer by regulating ferroptosis. @article{Liang2024ResearchSA, title={Research status and potential applications of circRNAs affecting colorectal cancer by regulating ferroptosis.}, author={Xiyuan Liang and Linna Long and Fan Guan and Zilu Xu and He Huang}, journal ...

  30. Colorectal cancer, screening and primary care: A mini literature review

    Core tip: Colorectal cancer (CRC) is a common health problem, causing a significant burden in terms of morbidity and mortality. However, if detected early, the disease is highly curable. Primary care physicians are therefore in a unique position to enhance prevention and prompt diagnosis. The purpose of this paper was to review the main topics ...