sample biology research paper

Sample Paper in Scientific Format

Biology 151/152.

The sample paper below has been compressed into the left-hand column on the pages below. In the right-hand column we have included notes explaining how and why the paper is written as it is.

Color Preferences for Nesting Material in the Zebra Finch ( )	The title should describe the study. In other words, the title should give the reader a good idea of the purpose of the experiment. Both the common and scientific names of the research organism must be included in the title.
INTRODUCTION
The zebra finch ( ) is a sexually dimorphic, social estrildid native to the grasslands of Australia. They are opportunistic, year-round breeders which nest in colonies of variable size. Zebra finches form permanent pair bonds and both sexes share the responsibilities of nest building, incubation and rearing of young (Walter, 1973). Morris (1954), however, reported that although both sexes pick up and nibble on fragments of material, males collect most of the nesting material.	The scientific name of the research organism must be stated the first time the organism is mentioned in any of the sections. Thereafter, within each section, either the common name or the abbreviated scientific name can be used.
Studies on the effects of colored plastic leg bands on pair formation show that male zebra finches spend more time sitting next to females wearing black or pink leg bands than females wearing light blue leg bands. The same studies indicate that females spend more time sitting next to males wearing red leg bands than males wearing light green bands. In both male and female, orange leg bands (which are similar to natural leg color) proved to be of intermediate preference (Burley, 1981 and 1982).	The first paragraphs of the introduction provide background information from preliminary or other published studies. This is used to develop the hypothesis or purpose of the experiment and to provide the rationale or reason for conducting the experiment.
The purpose of this study was to test whether or not this preference for certain colors of leg bands generalizes to preference for certain colors of nesting material. It was hypothesized that zebra finches would collect more red or black material than light green, with collection of orange being intermediate.	This paragraph specifically states the purpose of the experiment. It also states the hypothesis the author developed based on background reading and observations.
METHODS
The zebra finches used in this study were in three colonies in the lab of Dr. J.R. Baylis at the University of Wisconsin, Madison. Each colony contained between thirty and forty individual birds of both sexes, a variety of ages and several plumage types. All animals wore colored leg bands for individual identification and all had been exposed to grass, green embroidery floss and white dog fur as nesting material previous to this study. The colonies were housed in separate rooms, each approximately 17m3 and each contained eight artificial nest boxes. All behavioral observations were made from outside the colony rooms through one-way mirrors.	The methods begin by indicating where the research organisms were obtained. Specific examples about the organisms are included, e.g. number of organisms, sexes, ages, and morphology. Previous exposure to colored nest material is described. How organisms were housed, including specific dimensions of cages, etc. and the physical conditions of light and temperature, is also included.
Red, black, orange and light green DMC four-ply cotton embroidery floss was cut into 2.5 cm pieces. During each trial, twenty-five pieces of each color were separated and spread out over the floor of the colony. After the birds had been exposed to the material for a total of two hours, any remaining strands of floss on the floor were collected. The number of strands of each color was counted. It was assumed all other strands (not on the floor) had been used in nest construction. Data from the three colonies were pooled and an X goodness-of-fit test was used to determine whether the number of strands of each color used in nest construction different from an expected ratio of 1:1:1:1 (which would indicate no preference).	The types of test materials used are described in detail, as are the methods. Description of methods includes assumptions made and type of analysis to be performed on the data.

RESULTS
More green material was removed by the finches than red, more red than black and more black than orange. The ratio between material of different colors used in nest construction differed significantly from the expected 1:1:1:1 (X =63.44, df=3, p<.005). When colors were compared in pairs, the difference between values for green and red were not significantly different (X =117, df=1, p>.5). However, the values for black and orange were significantly different (X =36.38, df=1, p<.005).	The author interprets the data for the reader in text form. The author does not expect the reader to interpret the results from a table of data, but instead provides his/her interpretation for the reader.
DISCUSSION	The discussion provides an explanation of what the results mean relative to the original purpose and/or hypothesis stated in the introduction.
The results from these experiments suggest that zebra finches do in fact have color preferences with regard to nesting material. Contrary to the predictions made by generalizing Burley’s studies (1981, 1982), however, the zebra finches used in this study preferred green, red or black nesting material to orange. These results are similar to those of Collias and Collias (1981) who showed that weaver birds preferred green nesting material.	Results are compared to those from other studies. Plausible reasons/hypotheses are proposed to explain the results.
It is possible that zebra finches prefer green material to red, black and orange because green is more similar to the color of the grasses commonly used as nesting material in their natural environment. This interpretation, however, does not explain the preference for red and black materials over orange.	Limitations to the proposed hypotheses are also provided.
Alternatively, it is possible that the strong preference shown for green material may be a result of imprinting on the color of the nests they grew up in. It has been shown, for example, that parental plumage color has a strong effect on mate selection in male (but not female) zebra finches (Walter, 1973). All of the birds used in this study have been exposed to grass, green embroidery floss and white dog fur in nests. If as suggested by Morris (1954) males collect most of the nesting material, imprinting could have a strong effect on the numbers of colored strands collected in this study. This hypothesis could be tested by raising zebra finches in nests containing different colors of nesting materials and testing them in adulthood for preference in nest material color. When setting up this experiment, it was noted that zebra finches seem particularly apprehensive about new objects placed in the colony. It is also possible, therefore, that the preference for green nest material was simply due to its familiarity.	Alternative hypotheses are also provided, and evidence from literature is given in support of the alternate hypothesis. Future studies are proposed to help further knowledge in the area.
REFERENCES
Burley, N. 1981 Sex-ratio manipulation and selection for attractiveness. 211: 721-722. Burley, N. 1982 Influence of colour-banding on the nonspecific preference of zebra finches. . 30: 444-445. (Additional references deleted for brevity.)	All references cited in the body of the paper are listed alphabetically by last name of the first author. Only references cited in the body of the paper are listed here. See the Introductory Biology 151-152 manual for complete information on how to reference supporting literature both in the body of the paper and in the reference list.

Research Paper Writing Guides

Biology Research Paper Examples

Last updated on: May 14, 2024

Get Inspired by 10+ Biology Research Paper Examples

By: Dr. David Brown

Reviewed By:

Published on: May 9, 2024

Writing a biology research paper can be an overwhelming and highly complex process. Many students find it hard because there are so many steps to follow, from picking a topic to explaining their findings.

It's easy to feel lost or unsure about where to start. Especially without good examples to follow, it's easy to get stuck and not know what to do.

But don't worry! There's a helpful option that can make it all easier: Biology Research Paper Examples.

These are like blueprints that show us how to write a good paper. We'll explore these biology research examples together.

So, let's get started!

On this Page

How To Write A Biology Research Paper Examples

In this section, we'll explore some key elements of a biology research paper and provide examples to illustrate each point.

By studying these examples, you'll gain a better understanding of how to structure your paper, present your findings, and adhere to scientific conventions.

So let's begin by examining the different sections of a biology research paper and how examples can help you master each one.

Introduction

This section introduces your research topic, provides background information, and outlines the purpose of your study. It typically ends with a clear statement of your research question or hypothesis.

Here is an example for your better understanding:

Biology Research Paper Introduction Example

Materials and Methods

In this section, you describe the materials, equipment, and procedures used in your study. It should provide enough detail for other researchers to replicate your experiment or study.

To help you grasp the concept better, here's a biology research paper pdf:

Biology Research Paper Materials and Methods Example

Present your findings in this section, using tables, figures, or graphs to illustrate key data points. Describe any trends or patterns observed in the data.

Let's delve into a scientific paper sample pdf to clarify the concept:

Biology Research Paper Results Example

Discussion

Interpret the results of your study and discuss their significance in the context of existing literature. Address any limitations or potential biases in your research and propose areas for further investigation.

Here's an example to aid your understanding:

Biology Research Paper Discussion Example

Summarize the main findings of your study and emphasize their importance. Reflect on the implications of your research and suggest future directions for research in this area.

To illustrate the point more clearly, consider the following example:

Biology Research Paper Conclusion Example

Here are some more biology research paper examples:

Biology Research Paper Example High School

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Biology Research Paper Format Example

Interesting Biology Research Articles

Now that we've discussed the process of writing a biology research paper, let's explore some fascinating examples of research articles in the field of biology.

By examining these examples, you can gain insights into the latest discoveries, innovative methodologies, and pressing issues in the field.

Genome-Wide Analysis Identifies Molecular Systems And 149 Genetic Loci Associated With Income (In a study of 286,301 UK Biobank participants, 30 new genetic loci and 120 correlated loci were identified as associated with income, revealing links to neurotransmission and intelligence.)
Early Co-Authorship With Top Scientists Predicts Success In Academic Careers (Through matched pair analysis across four scientific disciplines, we found that junior researchers collaborating with highly-cited scientists enjoy long-term career advantages, including increased likelihood of future collaborations with top scientists and eventual attainment of high citation rates.)
Ketamine Can Reduce Harmful Drinking By Pharmacologically Rewriting Drinking Memories (We demonstrate that ketamine administration after the retrieval of maladaptive reward memories (MRMs) effectively disrupts such memories in hazardous drinkers.)
Sequential Laser Art And Crispr Treatments Eliminate Hiv-1 In A Subset Of Infected Humanized Mice (Sequential long-acting slow-effective release antiviral therapy (LASER ART) and CRISPR-Cas9 demonstrate viral clearance in latent infectious reservoirs in HIV-1 infected humanized mice, with elimination of integrated proviral DNA and absence of detectable virus in blood, lymphoid tissue, bone marrow, and brain.)
Ideological Differences In The Expanse Of The Moral Circle (Clashes between ideologies may reflect core psychological differences, as liberals tend to express compassion toward universal entities (universalism), while conservatives express compassion toward more well-defined entities (parochialism).

All in all, remember that biology research paper examples serve as invaluable tools for guiding you through the writing process, from formulating research questions to presenting your findings.

By incorporating examples into your learning, you can gain a deeper understanding of scientific writing conventions and develop the skills necessary to produce high-quality research papers.

And if you are ready to take your biology research paper to the next level? Visit SharkPapers.com for expert guidance, research paper editing services, and access to a vast library of research paper examples.

Dr. David Brown

Microbiology, Evolutionary Biology, Biotechnology

Dr. David Brown is a PhD holder in Biology from Cambridge University. He has over 9 years of experience in writing and editing research papers on various topics related to biology, such as genetics, ecology, evolution, and biotechnology. He is committed to helping students and researchers discover the wonders and mysteries of life and nature.

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Biological Research

ISSN: 0717-6287

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This document originally came from the Journal of Mammalogy courtesy of Dr. Ronald Barry, a former editor of the journal.

150 Actual Biology Research Paper Topics

Table of contents

1 What Is Biology? What Topics Might Biologists Study?
2 How to Choose a Topic for Biology Research Paper?
3.1 15 Developmental Biology Topics For Research
3.2 15 Immune System Biology Research Topics
3.3 15 Cell Biology Research Topics
3.4 15 DNA Research Topics
3.5 15 Molecular Biology Research Topics
3.6 15 Neurobiology Research Topics
3.7 15 Abortion, Human cloning, and Genetic Researches Topics
3.8 15 Environmental and Ecology Topics for Your Research
3.9 15 Plant Pathology Biology Research Topics
3.10 15 Animals Biology Research Topics
3.11 15 Marine Biology Research Topics
3.12 15 Zoology Research Topics
3.13 15 Genetics Research Topics
3.14 15 Biotechnology Research Topics
3.15 15 Evolutionary Biology Research Topics

Biology is one of the most magnetic fields of study these days. If you want to be a biologist or scientist in the future, there is no better time to start than right now. Biology research topics covered in this article will keep you busy and interested. Writing a research paper is one of the best ways to dip your toes into the field. Before doing that, you need to know some good topics for the research paper . They should be suitable for biology students rather than cutting-edge researchers. On Papersowl.com , we provide as many biology research paper examples as possible so that you have a huge choice.

What Is Biology? What Topics Might Biologists Study?

Biology is simply the study of everything that has a form of life. It includes investigations on plants, animals, and everything found in the environment. It is about studying how life forms grow, develop, and interact with each other. Biology essay topics for research encompass all these and more.

This science uncovers many fields where various life forms are studied. It makes sense to look through these fields to help you decide which suits you the best.

Plant Biology research topics are about studying the plants around us. They disclose information about their existence as a part of the ecosystem, their life cycle, resources they can give us, their ability to preserve them from climate changes, and so on. There are many ideas to choose from, but you must focus on a specific one.

Human Biology research topics are all about us. These topics focus on different body parts, such as the human brain, the human immunological system, the nervous system, etc. In addition, you can discuss DNA modifications in humans and explain why genetic disorders occur in your research projects. Various cell research is also common today.

Biology research topics on the environment are in great demand too. For example, climate change is becoming a more significant threat every day. By studying environmental topics in biology for projects and research, we can come up with ways to combat them and preserve ecosystems.

Microbiology research topics delve into things we can’t see. There are trillions of microbes and bacteria all around us. Knowing about them is essential to understanding what makes us sick and how to fight against them. All microbiology research paper topics are pretty complicated yet very engaging to include in your paper research.

Molecular biology topics dive even deeper into the level of atoms and molecules. The various medicines and drugs we take were all created through molecular-biology research. It is one of the areas full of ideas, but there is yet to be much evidence. Science is advancing in this realm but still needs a lot of time. Topics of molecular biology will need days for research only.

Keep in mind that there are more ideas and variations of this science. We offer more examples in further sections of the article about developmental biology, marine biology, evolutionary biology, etc. Explore them and make your writing appealing and meaningful in the eyes of a professor.

How to Choose a Topic for Biology Research Paper?

When choosing a biology project topic, you must be aware of one or more fields of science. Biology research is critical to the present world. By doing research, we can learn more about genetic disorders, immune disorders, mental health, natural disease resistance, etc. Knowing about each of these could save lives in the future.

For those who may not have the time or resources to do their own research, there are research paper writing services that can provide assistance with the project. And we are always here to help you find your own topic among interesting biology research topics. Here we prepared some useful tips to follow.

Tip 1: The level of interest matters Pay attention to one that interests you, and you might have ideas on how to develop the topic. Passion is fundamental in research, after all.
Tip 2: Explore the topic Try to narrow things down a bit. If the topic is too broad, you may not be able to cover all aspects of it in one research paper. If it is too narrow, the paper could end up too short. Analyze the topic and the ways to approach it. By doing so, you can strike a balance between the two.
Tip 3: Discover the recent developments To make your research paper touchable with the present day, you must explore the latest developments in the field. You can find out what kind of research has been done recently by looking at journals. Check out research papers, topics, research articles, and other sources.
Tip 4: Ensure to get enough resources When choosing a topic, make sure it has plenty of resources available. For example, a research paper on xenobiology or cutting-edge nanobiology might sound attractive. Still, you might have difficulties getting data and resources for those unless you are a researcher at a government lab. Data, resources, complex numbers, and statistics are all invaluable to writing a paper about these topics.

That is why we have selected a range of biological topics. The topics on this list are all hopefully exciting topics for research you could write an excellent paper on. We should also add that easy biology topics to research are rare, and a writer usually needs days to prepare and start writing. Yes, biology research topics for high school students are a bit easier, but still, they need time to explore them.

On the other hand, biology research topics for college students are far more complex and detailed. Some people prefer evolutionary biology research paper topics, and we can agree with this claim. These research areas do have a lot of potential and a lot of data to support the claims. Others prefer cell biology research topics that are a bit specific and fun. Anyway, with this article’s list of easy biology research topics, you will surely find the one matching your interest.

For those who may not have the time or resources to do their own research, there are provide assistance with the project.

15 Developmental Biology Topics For Research

Exploring the processes of how cells grow and develop is exciting. The human body contains millions of cells, and it’s interesting to research their behavior under different conditions. If you feel like writing about it, you can find some interesting biology topics below.

How do stem cells form different tissues?
How are tumors formed?
Duplication of genomes
Plasticity of development
Different birth defects
Interactions between genes and the environment
Anticancer drugs mixtures
Developmental diseases: Origin
Drosophila Oogenesis
Most deadly viruses
Most deadly bacteria in the world
How do germs affect cells?
How does leukemia start?
Development of the cardiovascular system in children
How do autoimmune diseases start and affect the human body?

15 Immune System Biology Research Topics

For decades, many scientists and immunologists have studied the human immune system and tried to explain its reaction to various pathogens. This area allows you to deepen into it and reveal how a body protects itself from harmful impact. Look over the biology research questions below and find your match-up.

How does the human body’s immune system work?
The human immune system: How to strengthen it?
What makes the immunological system weaker?
The notion of auto-immune diseases and their effect on the body’s immune system
The global HIV/aids epidemic
What methods are used to prevent the spread of hives?
Living with auto-immune diseases
Genetics and the immune system: effects and consequences
How do immune disorders affect the body, and what causes them?
Are allergies signs of worrying about an immune disorder?
DNA modification in solving immune disorders
Stress as the biggest ruiner of the immunological system
Vaccines as strong supporters of the immunological system
The perception of vaccines in society
Why do some people refuse vaccines and put others around them in danger?

15 Cell Biology Research Topics

Cell study might seem challenging yet very engaging. It will be a good idea to compare various types of cells and compare them in animals and plants. Make your choice from the list of cell biology research topics below.

The structure of an animal cell
Mitochondria and its meaning in cell development
Cells classification and their functions
Red blood cells and their function in transporting oxygen
White blood cells and their responsibility to fight diseases
How are plant cells different from animal cells?
What would it be if animals had a function to photosynthesize?
Single-celled organisms: What is it, and how do they work?
What processes do cells go through in division?
Invasion of bacteria into the body
Viruses – alive or not?
Fungi: their reproduction and distribution
Cancer cells: Why are they so dangerous?
What methods are used to kill cancer cells?
The role of stem cells and their potential in a body

15 DNA Research Topics

The variety of biology research topics for college students might impress you a lot. This is a science with a large field of investigation, disclosing much scientific information to use in your project. The notion of DNA and its gist are also excellent options to write about.

The structure of the human DNA
The main components of a DNA chain
Why does DNA have a double-helix spiral structure?
The purpose of chromosomes
MRNA and its relation to DNA
Do single-celled organisms have DNA?
Do viruses have DNA?
What happens if you have too many or too few chromosomes?
Analyzing the structure of DNA using computers
Uses for the DNA of extinct organisms like mammoths and dinosaurs
Storing non-genetic information in DNA
Can you write a computer program into human DNA?
How does radiation affect DNA?
Modifying DNA to treat aids
Can we fight cancer through DNA modification?

15 Molecular Biology Research Topics

Do you prefer to research molecules’ chemical and physical composition? We gathered some molecular biology research topics to make your choice easier.

The structure and components of a gene
How do molecules move in and out of a cell?
The basic building blocks of life
How are drugs designed for humans?
How is a vaccine designed to target a specific disease?
Dominant genes vs. recessive genes
Prion disease – why is it so dangerous?
Hormones and their function in the body
Developing artificial hormones from other animals
How to carry out a western blot?
Testing and analyzing DNA using PCR
The three-dimensional structure of a molecule
What is DNA transcription, and how is it used?
The structure of a prion
What is the central dogma of molecular biology?

15 Neurobiology Research Topics

The more you dive into science, the more exciting things you find. That’s about biology. Here, you can choose biology research topics for high school and try to reveal more simply.

Nervous system: its structure and function
Neurons as unique cells playing a central role in the nervous system
What is the maximum reaction speed in a human?
Reaction speed: how to improve it?
Research on Organic Farming
What are the symptoms of Alzheimer’s disease?
Why do we feel happy or sad?
Headaches in terms of Neurobiology
What are the reasons for neurobiological degeneration?
Myths and reality of Amnesia
What causes Alzheimer’s Disease, and what are the consequences of the disease?
What is the treatment for Spinal Cord Injury?
Studies on Narcolepsy and Insomnia: What are the causes?
Is there a connection between Mental Health and Neurobiology?
Emotions in terms of their reflection in the brain

15 Abortion, Human cloning, and Genetic Researches Topics

There are so many scientific researches and theories that society accepts or neglects. You can operate different notions and try to explain them, reflecting their advantages and downsides for a human being. We gathered some enticing life science research topics for high school students that might interest you.

The controversy around abortion: legal or not?
Can abortion be safe?
Human cloning – reality vs. science-fiction
The goals of cloning humans
Are human cloning and transplantation ethical?
Having a “perfect child” through gene therapy: Is it a myth?
How far has gene therapy gone in genetic research?
Advantages and disadvantages of gene therapy
How gene therapy can help beat cancer
How gene therapy can eliminate diabetes
The opportunity to edit genes by CRISPR
DNA modifications in humans to enhance our abilities – an ethical dilemma
Will expensive gene therapy widen the gap between the rich and the poor?
Cloning: the good and the Bad for a Generation
The disadvantages of cloning
Free unlimited checks
All common file formats
Accurate results
Intuitive interface

15 Environmental and Ecology Topics for Your Research

The nature around us is so enormous and includes many branches to investigate. If you are keen on the environment and how ecology affects it, the list of follow-up biology paper topics might be helpful to you.

The theory of evolution
How does natural selection work?
How do living organisms adapt to their environment?
The concept of divergent and convergent evolution
Building a sustainable environment
Development of environment-friendly cities
How to control population growth?
Why have recycling resources become so essential in the modern world?
The effect of plastic on the environment
What are the global consequences of deforestation?
What can we expect when losing biodiversity?
Ecological damage: How to prevent it?
How can GMO products affect ecology?
Cloning endangered or extinct species: Is it a good idea?
Is climate change the main reason for disrupting ecology?

15 Plant Pathology Biology Research Topics

Many factors impact human health and the quality of food products matters. These easy biology research topics will be useful if you want to describe the connection between those two concepts.

How do plants protect themselves from diseases?
How to increase the plant’s resistance to diseases?
Diseases distribution among plants
The banana pandemic
How do herbicides influence plants?
Corn blight
Can any plant diseases affect humans?
The issue of stem rust and its impact on wheat
What approaches are used to struggle against invasive plants and affected weeds?
Fertilizers: their pros and cons on plants
Plant disease genetics: its system and structure
What is the connection between ecological changes and plant diseases?
Modifications on food production because of plant diseases
How do fungal and viral diseases appear in plants?
The sweet potato virus

15 Animals Biology Research Topics

It’s hard to find someone who doesn’t like animals. If you are curious about animals scientifically, here you are with biology research paper topics in this field.

Classification of animals
Land-based life: its evolution history
Controversies about keeping animals as pets
Is it ethical to test drugs and products on animals?
Why do nature reserves against zoos?
Evidence on prehistoric aquatic animals growing giant
What species of animals are vegan?
Animals and their social behavior
Primate behavior
How intelligent can other primates be?
Are wolves and dogs intelligent?
Domesticating animals
Hibernation in animals
Why animals migrate
Should we bring back extinct animals?

15 Marine Biology Research Topics

The marine theme is engaging as it reveals so many interesting facts about life forms dwelling under the water. You can make your paper look captivating using biology topics in marine below.

How acidification affects aquatic environments
Evolution in the deep sea
What’s the meaning of camouflage mechanism in sea life?
Consequences of oil spills on marine life
Oldest marine species
How do whales communicate with each other?
How blind fish navigate
Are marine shows and aquariums ethical?
The biology and life cycle of seabirds
How jellyfish are immortal
Plankton ecology
Difference between freshwater and seawater marine life
Coral reefs: their importance and evolution
Saving and restoring coral reefs
Life in the deep-sea ocean trenches

15 Zoology Research Topics

Zoology can be an excellent choice to write about if you are close to animal studies. Look at biology topics to research and choose the one that fits your interest most.

Asian elephants and human speech patterns
Oyster genomes and adaptation
Darwin’s work in the Galápagos Islands
Asian carp: Invasive species analysis
Giant squids: Fact vs. fiction
Coyote and wolf hybrid species in the United States
Parasites and disease
Migration patterns of killer bees
The treatment of species in Melville’s Moby Dick
Biodiversity and plankton
The role of camels and the development of Africa and the Middle East
Muskellunge and adaptive creek mechanisms to small water
Ants and cooperative behavior among species
Animal communication and the origin of language
Speech in African Gray Parrots

15 Genetics Research Topics

Writing about modifications caused on the gene level is pretty challenging but very fascinating. You can select one among the biological questions for research and bring up a meaningful paper.

Genetics and its role in cancer studies
Can genetic code be confidential?
Is it possible to choose the sex of a person before birth?
Genetics as a ray of hope for children with an intellectual disability
What factors in human genetics affect behavior?
Is it somehow possible to improve human personality through genetics?
Are there any living cells in the gene?
Fighting HIV with gene mutations
Genetic mutations
How addictive substances affect genes
Genetic testing: is it necessary?
Cloning: positive or negative outcome for future generations
Pros and cons of genetic engineering
Is the world ready for the bioethics revolution?
The linkage between genetics and obesity

15 Biotechnology Research Topics

The way scientists conduct research today is magnificent. Implementing high-tech innovations in biology research brings new opportunities to study the world. What are these opportunities? Explore biotechnology research topics for college students and disclose the best options for you.

Biotechnology used in plant research
What is the contribution of biotechnology to food?
Pharmacogenetics: What is it, and how it works?
How are anti-cancer drugs produced to be effective?
Nanotechnology in DNA: How to isolate it?
Recent nanotechnology used in HIV treatment
What biotech apps are used to detect foodborne pathogens in food systems?
Genotypes research: Why are they tolerant and sensitive to heavy metal?
High-tech solutions in diagnosing cancer
Forensic DNA and its latest developments
Metabolic changes at the level of cells
Nanotechnology in improving treatments for respiratory viruses
The latest biotech discoveries
Digital evolution: bioresearch and its transformation
The concept of vaccine development

15 Evolutionary Biology Research Topics

Knowing how life forms started their existence is fundamental. And more interesting is to look through the evolution of many processes. If you find this trend of research more engaging, we outlined evolutionary biology research paper topics to diversify your choice.

Darwin’s concept’s impact on science
The evolution concept by Lamarck
Origins of the evolutionary theory
Evolution acceptance: a belief vs. a theory?
Evolutionary in microbiology
Development of robotics
Revealing differences: human brain & animal brain
Preservation of biological resources
Transformations in aging
Adaptive genetic system
Morphometrics’ history
Developmental theory and population genomics
Bacteria ecology’s evolution
Biological changes: impact and evolution
Infectious diseases and their profession

The world of science and biology is vast, making research tedious. Use our list of interesting biology research topics to choose the best issue to write your own paper.

However, it is still hard to prepare a high-quality biology research paper, even with a brilliant topic. Not all college students can do it. Do you feel like you need some help? Then buy biology paper from our professional writers! Our experts will choose the best biology experimental research topics for you and can bring up top-level papers within the shortest time. Additionally, if you need help with a statistics project related to biology, our team of experienced professionals is equipped to provide you with the utmost quality of research and analysis.

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Collection 12 March 2020

Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

Household income is used as a marker of socioeconomic position, a trait that is associated with better physical and mental health. Here, Hill et al. report a genome-wide association study for household income in the UK and explore its relationship with intelligence in post-GWAS analyses including Mendelian randomization.

W. David Hill
Neil M. Davies
Ian J. Deary

A 5700 year-old human genome and oral microbiome from chewed birch pitch

Birch pitch is thought to have been used in prehistoric times as hafting material or antiseptic and tooth imprints suggest that it was chewed. Here, the authors report a 5,700 year-old piece of chewed birch pitch from Denmark from which they successfully recovered a complete ancient human genome and oral microbiome DNA.

Theis Z. T. Jensen
Jonas Niemann
Hannes Schroeder

A short translational ramp determines the efficiency of protein synthesis

Several factors contribute to the efficiency of protein expression. Here the authors show that the identity of amino acids encoded by codons at position 3–5 significantly impact translation efficiency and protein expression levels.

Manasvi Verma
Junhong Choi
Sergej Djuranovic

Early coauthorship with top scientists predicts success in academic careers

By examining publication records of scientists from four disciplines, the authors show that coauthoring a paper with a top-cited scientist early in one's career predicts lasting increases in career success, especially for researchers affiliated with less prestigious institutions.

Tomaso Aste
Giacomo Livan

Ancient DNA from the skeletons of Roopkund Lake reveals Mediterranean migrants in India

Remains of several hundred humans are scattered around Roopkund Lake, situated over 5,000 meters above sea level in the Himalayan Mountains. Here the authors analyze genome-wide data from 38 skeletons and find 3 clusters with different ancestries and dates, showing the people were desposited in multiple catastrophic events.

Éadaoin Harney
Ayushi Nayak

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolidation of these memories and reduces drinking in humans.

Ravi K. Das
Sunjeev K. Kamboj

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

Here, the authors show that sequential treatment with long-acting slow-effective release ART and AAV9- based delivery of CRISPR-Cas9 results in undetectable levels of virus and integrated DNA in a subset of humanized HIV-1 infected mice. This proof-of-concept study suggests that HIV-1 elimination is possible.

Prasanta K. Dash
Rafal Kaminski
Howard E. Gendelman

XX sex chromosome complement promotes atherosclerosis in mice

Men and women differ in their risk of developing coronary artery disease, in part due to differences in their levels of sex hormones. Here, AlSiraj et al. show that the XX sex genotype regulates lipid metabolism and promotes atherosclerosis independently of sex hormones in mice.

Yasir AlSiraj
Lisa A. Cassis

Early-career setback and future career impact

Little is known about the long-term effects of early-career setback. Here, the authors compare junior scientists who were awarded a NIH grant to those with similar track records, who were not, and find that individuals with the early setback systematically performed better in the longer term.

Benjamin F. Jones
Dashun Wang

Ideological differences in the expanse of the moral circle

How do liberals and conservatives differ in their expression of compassion and moral concern? The authors show that conservatives tend to express concern toward smaller, more well-defined, and less permeable social circles, while liberals express concern toward larger, less well-defined, and more permeable social circles.

Jesse Graham

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

Biomarkers that predict mortality are of interest for clinical as well as research applications. Here, the authors analyze metabolomics data from 44,168 individuals and identify key metabolites independently associated with all-cause mortality risk.

Joris Deelen
Johannes Kettunen
P. Eline Slagboom

New insects feeding on dinosaur feathers in mid-Cretaceous amber

Numerous feathered dinosaurs and early birds have been discovered from the Jurassic and Cretaceous, but the early evolution of feather-feeding insects is not clear. Here, Gao et al. describe a new family of ectoparasitic insects from 10 specimens found associated with feathers in mid-Cretaceous amber.

Taiping Gao
Xiangchu Yin

Acoustic enrichment can enhance fish community development on degraded coral reef habitat

Healthy coral reefs have an acoustic signature known to be attractive to coral and fish larvae during settlement. Here the authors use playback experiments in the field to show that healthy reef sounds can increase recruitment of juvenile fishes to degraded coral reef habitat, suggesting that acoustic playback could be used as a reef management strategy.

Timothy A. C. Gordon
Andrew N. Radford
Stephen D. Simpson

Phagocytosis-like cell engulfment by a planctomycete bacterium

Phagocytosis is a typically eukaryotic feature that could be behind the origin of eukaryotic cells. Here, the authors describe a bacterium that can engulf other bacteria and small eukaryotic cells through a phagocytosis-like mechanism.

Takashi Shiratori
Shigekatsu Suzuki
Ken-ichiro Ishida

Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation

The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.

Shunsuke Hasegawa
Hotaka Fukushima
Satoshi Kida

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

Integrating independent large-scale pharmacogenomic screens can enable unprecedented characterization of genetic vulnerabilities in cancers. Here, the authors show that the two largest independent CRISPR-Cas9 gene-dependency screens are concordant, paving the way for joint analysis of the data sets.

Joshua M. Dempster
Clare Pacini
Francesco Iorio

Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea

The authors build a reference phylogeny of 10,575 evenly-sampled bacterial and archaeal genomes, based on 381 markers. The results indicate a remarkably closer evolutionary proximity between Archaea and Bacteria than previous estimates that used fewer “core” genes, such as the ribosomal proteins.

Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers

Mass-spectrometry-based profiling can be used to stratify tumours into molecular subtypes. Here, by classifying over 500 tumours, the authors show that this approach reveals proteomic subgroups which cut across tumour types.

Fengju Chen
Darshan S. Chandrashekar
Chad J. Creighton

CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci

Inducible genome editing systems often suffer from leakiness or reduced activity. Here the authors develop CRISPR-Switch, a Cre recombinase ON/OFF-controlled sgRNA cassette that allows consecutive editing of two loci.

Krzysztof Chylinski
Maria Hubmann
Ulrich Elling

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Class 1 CRISPR systems are not as developed for genome editing as Class 2 systems are. Here the authors show that Cas3 can be used to generate functional knockouts and knock-ins, as well as Cas3-mediated exon-skipping in DMD cells.

Hiroyuki Morisaka
Kazuto Yoshimi
Tomoji Mashimo

Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

From observational studies, alcohol consumption behaviours are known to be correlated in spouses. Here, Howe et al. use partners’ genotypic information in a Mendelian randomization framework and show that a SNP in the ADH1B gene associates with partner’s alcohol consumption, suggesting that alcohol consumption affects mate choice.

Laurence J. Howe
Daniel J. Lawson
Gibran Hemani

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy

While the cellular recycling process autophagy has been linked to aging, the impact of selective autophagy on lifespan remains unclear. Here Kumsta et al. show that the autophagy receptor p62/SQSTM1 is required for hormetic benefits and p62/SQSTM1 overexpression is sufficient to extend C. elegans lifespan and improve proteostasis.

Caroline Kumsta
Jessica T. Chang
Malene Hansen

The coincidence of ecological opportunity with hybridization explains rapid adaptive radiation in Lake Mweru cichlid fishes

Recent studies have suggested that hybridization can facilitate adaptive radiations. Here, the authors show that opportunity for hybridization differentiates Lake Mweru, where cichlids radiated, and Lake Bangweulu, where cichlids did not radiate despite ecological opportunity in both lakes.

Joana I. Meier
Rike B. Stelkens
Ole Seehausen

Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases

Gut microbiota alterations, including enrichment of flagellated bacteria, are associated with metabolic syndrome and chronic inflammatory diseases. Here, Tran et al. show, in mice, that elicitation of mucosal anti-flagellin antibodies protects against experimental colitis and ameliorates diet-induced obesity.

Hao Q. Tran
Ruth E. Ley
Benoit Chassaing

Possible role of L-form switching in recurrent urinary tract infection

The reservoir for recurrent urinary tract infection in humans is unclear. Here, Mickiewicz et al. detect cell-wall deficient (L-form) E. coli in fresh urine from patients, and show that the isolated bacteria readily switch between walled and L-form states.

Katarzyna M. Mickiewicz
Yoshikazu Kawai
Jeff Errington

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Although it is known that microglia respond to injury and systemic disease in the brain, it is unclear if they modulate blood–brain barrier (BBB) integrity, which is critical for regulating neuroinflammatory responses. Here authors demonstrate that microglia respond to inflammation by migrating towards and accumulating around cerebral vessels, where they initially maintain BBB integrity via expression of the tight-junction protein Claudin-5 before switching, during sustained inflammation, to phagocytically remove astrocytic end-feet resulting in impaired BBB function

Koichiro Haruwaka
Ako Ikegami
Hiroaki Wake

Mice with hyper-long telomeres show less metabolic aging and longer lifespans

Telomere shortening is associated with aging. Here the authors analyze mice with hyperlong telomeres and demonstrate that longer telomeres than normal have beneficial effects such as delayed metabolic aging, increased longevity and less incidence of cancer.

Miguel A. Muñoz-Lorente
Alba C. Cano-Martin
Maria A. Blasco

Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

Organoid cultures have been developed from multiple tissues, opening new possibilities for regenerative medicine. Here the authors demonstrate the derivation of GMP-compliant hydrogels from decellularized porcine small intestine which support formation and growth of human gastric, liver, pancreatic and small intestinal organoids.

Giovanni Giuseppe Giobbe
Claire Crowley
Paolo De Coppi

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

Anti-inflammatory treatments for gastrointestinal diseases can often have detrimental side effects. Here the authors engineer E. coli Nissle 1917 to create a fibrous matrix that has a protective effect in DSS-induced colitis mice.

Pichet Praveschotinunt
Anna M. Duraj-Thatte
Neel S. Joshi

Ambient black carbon particles reach the fetal side of human placenta

Exposure to air pollution during pregnancy has been associated with impaired birth outcomes. Here, Bové et al. report evidence of black carbon particle deposition on the fetal side of human placentae, including at early stages of pregnancy, suggesting air pollution could affect birth outcome through direct effects on the fetus.

Hannelore Bové
Eva Bongaerts
Tim S. Nawrot

Real-time decoding of question-and-answer speech dialogue using human cortical activity

Speech neuroprosthetic devices should be capable of restoring a patient’s ability to participate in interactive dialogue. Here, the authors demonstrate that the context of a verbal exchange can be used to enhance neural decoder performance in real time.

David A. Moses
Matthew K. Leonard
Edward F. Chang

In-cell identification and measurement of RNA-protein interactions

RNA-interacting proteome can be identified by RNA affinity purification followed by mass spectrometry. Here the authors developed a different RNA-centric technology that combines high-throughput immunoprecipitation of RNA binding proteins and luciferase-based detection of their interaction with the RNA.

Antoine Graindorge
Inês Pinheiro
Alena Shkumatava

A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus

Genedrives bias the inheritance of alleles in diploid organisms. Here, the authors develop a gene-drive analogous system for bacteria, selectively editing and clearing plasmids.

J. Andrés Valderrama
Surashree S. Kulkarni

Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort

The studies showing health benefits of flavonoids and their impact on cancer mortality are incomplete. Here, the authors perform a prospective cohort study in Danish participants and demonstrate an inverse association between regular flavonoid intake and both cardiovascular and cancer related mortality.

Nicola P. Bondonno
Frederik Dalgaard
Jonathan M. Hodgson

Senescent cell turnover slows with age providing an explanation for the Gompertz law

One of the underlying causes of aging is the accumulation of senescent cells, but their turnover rates and dynamics during ageing are unknown. Here the authors measure and model senescent cell production and removal and explore implications for mortality.

Amit Agrawal

Optimizing agent behavior over long time scales by transporting value

People are able to mentally time travel to distant memories and reflect on the consequences of those past events. Here, the authors show how a mechanism that connects learning from delayed rewards with memory retrieval can enable AI agents to discover links between past events to help decide better courses of action in the future.

Chia-Chun Hung
Timothy Lillicrap

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Ageing is associated with clonal hematopoiesis of indeterminate potential (CHIP), which is linked to increased risks of hematological malignancies. Here the authors uncover an epigenetic mechanism through which mutant p53 drives clonal hematopoiesis through interaction with EZH2.

A systematic evaluation of single cell RNA-seq analysis pipelines

There has been a rapid rise in single cell RNA-seq methods and associated pipelines. Here the authors use simulated data to systematically evaluate the performance of 3000 possible pipelines to derive recommendations for data processing and analysis of different types of scRNA-seq experiments.

Beate Vieth
Swati Parekh
Ines Hellmann

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue

Alzheimer’s disease is characterised by the deposition of Aβ amyloid fibrils and tau protein neurofibrillary tangles. Here the authors use cryo-EM to structurally characterise brain derived Aβ amyloid fibrils and find that they are polymorphic and right-hand twisted, which differs from in vitro generated Aβ fibrils.

Marius Kollmer
William Close
Marcus Fändrich

Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes

Culturing transposon-mutant libraries in pools can mask complex phenotypes. Here the authors present microfluidics mediated droplet Tn-Seq, which encapsulates individual mutants, promotes isolated growth and enables cell-cell interaction analyses.

Derek Thibault
Paul A. Jensen
Tim van Opijnen

An artificial metalloenzyme biosensor can detect ethylene gas in fruits and Arabidopsis leaves

Existing methods to detect ethylene in plant tissue typically require gas chromatography or use ethylene-dependent gene expression as a proxy. Here Vong et al . show that an artificial metalloenzyme-based ethylene probe can be used to detect ethylene in plants with improved spatiotemporal resolution.

Kenward Vong
Katsunori Tanaka

Artificially cloaked viral nanovaccine for cancer immunotherapy

Cancer therapy using oncolytic virus has shown pre-clinical and clinical efficacy. Here, the authors report ExtraCRAd, an oncolytic virus cloaked with tumour cell membrane and report its therapeutic effects in vitro and in vivo in multiple mouse tumour models.

Manlio Fusciello
Flavia Fontana
Vincenzo Cerullo

A transposable element insertion is associated with an alternative life history strategy

Tradeoffs are central to life history theory and evolutionary biology, yet almost nothing is known about their mechanistic basis. Here the authors characterize one such mechanism and find a transposable element insertion is associated with the switch between alternative life history strategies.

Alyssa Woronik
Kalle Tunström
Christopher W. Wheat

Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula

The Iberian Peninsula has a complex history. Here, the authors analyse the genetic structure of the modern Iberian population at fine scale, revealing historical population movements associated with the time of Muslim rule.

Clare Bycroft
Ceres Fernandez-Rozadilla
Simon Myers

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

Immune cells are shaped by the tissue environment, yet the states of healthy human T cells are mainly studied in the blood. Here, the authors perform single cell RNA-seq of T cells from tissues and blood of healthy donors and show its utility as a reference map for comparison of human T cell states in disease.

Peter A. Szabo
Hanna Mendes Levitin
Peter A. Sims

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

Stroke risk is influenced by genetic and lifestyle factors and previously a genomic risk score (GRS) for stroke was proposed, albeit with limited predictive power. Here, Abraham et al. develop a metaGRS that is composed of several stroke-related GRSs and demonstrate improved predictive power compared with individual GRS or classic risk factors.

Gad Abraham
Rainer Malik
Martin Dichgans

Mitochondrial oxidative capacity and NAD + biosynthesis are reduced in human sarcopenia across ethnicities

Sarcopenia is the loss of muscle mass and strength associated with physical disability during ageing. Here, the authors analyse muscle biopsies from 119 patients with sarcopenia and age-matched controls of different ethnic groups and find transcriptional signatures indicating mitochondrial dysfunction, associated with reduced mitochondria numbers and lower NAD + levels in older individuals with sarcopenia.

Eugenia Migliavacca
Stacey K. H. Tay
Jerome N. Feige

NAD + augmentation restores mitophagy and limits accelerated aging in Werner syndrome

The molecular mechanisms of mitochondrial dysfunction in the premature ageing Werner syndrome were elusive. Here the authors show that NAD + depletion-induced impaired mitophagy contributes to this phenomenon, shedding light on potential therapeutics.

Evandro F. Fang
Vilhelm A. Bohr

Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells

Single strand breaks represent the most common form of DNA damage yet no methods to map them in a genome-wide fashion at single nucleotide resolution exist. Here the authors develop such a method and apply to uncover patterns of single-strand DNA “breakome” in different biological conditions.

Lorena Salazar-García
Philipp Kapranov

Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis

Here, the authors explore the potential of the 16S gene for discriminating bacterial taxa and show that full-length sequencing combined with appropriate clustering of intragenomic sequence variation can provide accurate representation of bacterial species in microbiome datasets.

Jethro S. Johnson
Daniel J. Spakowicz
George M. Weinstock

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