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500+ Quantitative Research Titles and Topics

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Quantitative Research Topics

Quantitative research involves collecting and analyzing numerical data to identify patterns, trends, and relationships among variables. This method is widely used in social sciences, psychology , economics , and other fields where researchers aim to understand human behavior and phenomena through statistical analysis. If you are looking for a quantitative research topic, there are numerous areas to explore, from analyzing data on a specific population to studying the effects of a particular intervention or treatment. In this post, we will provide some ideas for quantitative research topics that may inspire you and help you narrow down your interests.

Quantitative Research Titles

Quantitative Research Titles are as follows:

Business and Economics

  • “Statistical Analysis of Supply Chain Disruptions on Retail Sales”
  • “Quantitative Examination of Consumer Loyalty Programs in the Fast Food Industry”
  • “Predicting Stock Market Trends Using Machine Learning Algorithms”
  • “Influence of Workplace Environment on Employee Productivity: A Quantitative Study”
  • “Impact of Economic Policies on Small Businesses: A Regression Analysis”
  • “Customer Satisfaction and Profit Margins: A Quantitative Correlation Study”
  • “Analyzing the Role of Marketing in Brand Recognition: A Statistical Overview”
  • “Quantitative Effects of Corporate Social Responsibility on Consumer Trust”
  • “Price Elasticity of Demand for Luxury Goods: A Case Study”
  • “The Relationship Between Fiscal Policy and Inflation Rates: A Time-Series Analysis”
  • “Factors Influencing E-commerce Conversion Rates: A Quantitative Exploration”
  • “Examining the Correlation Between Interest Rates and Consumer Spending”
  • “Standardized Testing and Academic Performance: A Quantitative Evaluation”
  • “Teaching Strategies and Student Learning Outcomes in Secondary Schools: A Quantitative Study”
  • “The Relationship Between Extracurricular Activities and Academic Success”
  • “Influence of Parental Involvement on Children’s Educational Achievements”
  • “Digital Literacy in Primary Schools: A Quantitative Assessment”
  • “Learning Outcomes in Blended vs. Traditional Classrooms: A Comparative Analysis”
  • “Correlation Between Teacher Experience and Student Success Rates”
  • “Analyzing the Impact of Classroom Technology on Reading Comprehension”
  • “Gender Differences in STEM Fields: A Quantitative Analysis of Enrollment Data”
  • “The Relationship Between Homework Load and Academic Burnout”
  • “Assessment of Special Education Programs in Public Schools”
  • “Role of Peer Tutoring in Improving Academic Performance: A Quantitative Study”

Medicine and Health Sciences

  • “The Impact of Sleep Duration on Cardiovascular Health: A Cross-sectional Study”
  • “Analyzing the Efficacy of Various Antidepressants: A Meta-Analysis”
  • “Patient Satisfaction in Telehealth Services: A Quantitative Assessment”
  • “Dietary Habits and Incidence of Heart Disease: A Quantitative Review”
  • “Correlations Between Stress Levels and Immune System Functioning”
  • “Smoking and Lung Function: A Quantitative Analysis”
  • “Influence of Physical Activity on Mental Health in Older Adults”
  • “Antibiotic Resistance Patterns in Community Hospitals: A Quantitative Study”
  • “The Efficacy of Vaccination Programs in Controlling Disease Spread: A Time-Series Analysis”
  • “Role of Social Determinants in Health Outcomes: A Quantitative Exploration”
  • “Impact of Hospital Design on Patient Recovery Rates”
  • “Quantitative Analysis of Dietary Choices and Obesity Rates in Children”

Social Sciences

  • “Examining Social Inequality through Wage Distribution: A Quantitative Study”
  • “Impact of Parental Divorce on Child Development: A Longitudinal Study”
  • “Social Media and its Effect on Political Polarization: A Quantitative Analysis”
  • “The Relationship Between Religion and Social Attitudes: A Statistical Overview”
  • “Influence of Socioeconomic Status on Educational Achievement”
  • “Quantifying the Effects of Community Programs on Crime Reduction”
  • “Public Opinion and Immigration Policies: A Quantitative Exploration”
  • “Analyzing the Gender Representation in Political Offices: A Quantitative Study”
  • “Impact of Mass Media on Public Opinion: A Regression Analysis”
  • “Influence of Urban Design on Social Interactions in Communities”
  • “The Role of Social Support in Mental Health Outcomes: A Quantitative Analysis”
  • “Examining the Relationship Between Substance Abuse and Employment Status”

Engineering and Technology

  • “Performance Evaluation of Different Machine Learning Algorithms in Autonomous Vehicles”
  • “Material Science: A Quantitative Analysis of Stress-Strain Properties in Various Alloys”
  • “Impacts of Data Center Cooling Solutions on Energy Consumption”
  • “Analyzing the Reliability of Renewable Energy Sources in Grid Management”
  • “Optimization of 5G Network Performance: A Quantitative Assessment”
  • “Quantifying the Effects of Aerodynamics on Fuel Efficiency in Commercial Airplanes”
  • “The Relationship Between Software Complexity and Bug Frequency”
  • “Machine Learning in Predictive Maintenance: A Quantitative Analysis”
  • “Wearable Technologies and their Impact on Healthcare Monitoring”
  • “Quantitative Assessment of Cybersecurity Measures in Financial Institutions”
  • “Analysis of Noise Pollution from Urban Transportation Systems”
  • “The Influence of Architectural Design on Energy Efficiency in Buildings”

Quantitative Research Topics

Quantitative Research Topics are as follows:

  • The effects of social media on self-esteem among teenagers.
  • A comparative study of academic achievement among students of single-sex and co-educational schools.
  • The impact of gender on leadership styles in the workplace.
  • The correlation between parental involvement and academic performance of students.
  • The effect of mindfulness meditation on stress levels in college students.
  • The relationship between employee motivation and job satisfaction.
  • The effectiveness of online learning compared to traditional classroom learning.
  • The correlation between sleep duration and academic performance among college students.
  • The impact of exercise on mental health among adults.
  • The relationship between social support and psychological well-being among cancer patients.
  • The effect of caffeine consumption on sleep quality.
  • A comparative study of the effectiveness of cognitive-behavioral therapy and pharmacotherapy in treating depression.
  • The relationship between physical attractiveness and job opportunities.
  • The correlation between smartphone addiction and academic performance among high school students.
  • The impact of music on memory recall among adults.
  • The effectiveness of parental control software in limiting children’s online activity.
  • The relationship between social media use and body image dissatisfaction among young adults.
  • The correlation between academic achievement and parental involvement among minority students.
  • The impact of early childhood education on academic performance in later years.
  • The effectiveness of employee training and development programs in improving organizational performance.
  • The relationship between socioeconomic status and access to healthcare services.
  • The correlation between social support and academic achievement among college students.
  • The impact of technology on communication skills among children.
  • The effectiveness of mindfulness-based stress reduction programs in reducing symptoms of anxiety and depression.
  • The relationship between employee turnover and organizational culture.
  • The correlation between job satisfaction and employee engagement.
  • The impact of video game violence on aggressive behavior among children.
  • The effectiveness of nutritional education in promoting healthy eating habits among adolescents.
  • The relationship between bullying and academic performance among middle school students.
  • The correlation between teacher expectations and student achievement.
  • The impact of gender stereotypes on career choices among high school students.
  • The effectiveness of anger management programs in reducing violent behavior.
  • The relationship between social support and recovery from substance abuse.
  • The correlation between parent-child communication and adolescent drug use.
  • The impact of technology on family relationships.
  • The effectiveness of smoking cessation programs in promoting long-term abstinence.
  • The relationship between personality traits and academic achievement.
  • The correlation between stress and job performance among healthcare professionals.
  • The impact of online privacy concerns on social media use.
  • The effectiveness of cognitive-behavioral therapy in treating anxiety disorders.
  • The relationship between teacher feedback and student motivation.
  • The correlation between physical activity and academic performance among elementary school students.
  • The impact of parental divorce on academic achievement among children.
  • The effectiveness of diversity training in improving workplace relationships.
  • The relationship between childhood trauma and adult mental health.
  • The correlation between parental involvement and substance abuse among adolescents.
  • The impact of social media use on romantic relationships among young adults.
  • The effectiveness of assertiveness training in improving communication skills.
  • The relationship between parental expectations and academic achievement among high school students.
  • The correlation between sleep quality and mood among adults.
  • The impact of video game addiction on academic performance among college students.
  • The effectiveness of group therapy in treating eating disorders.
  • The relationship between job stress and job performance among teachers.
  • The correlation between mindfulness and emotional regulation.
  • The impact of social media use on self-esteem among college students.
  • The effectiveness of parent-teacher communication in promoting academic achievement among elementary school students.
  • The impact of renewable energy policies on carbon emissions
  • The relationship between employee motivation and job performance
  • The effectiveness of psychotherapy in treating eating disorders
  • The correlation between physical activity and cognitive function in older adults
  • The effect of childhood poverty on adult health outcomes
  • The impact of urbanization on biodiversity conservation
  • The relationship between work-life balance and employee job satisfaction
  • The effectiveness of eye movement desensitization and reprocessing (EMDR) in treating trauma
  • The correlation between parenting styles and child behavior
  • The effect of social media on political polarization
  • The impact of foreign aid on economic development
  • The relationship between workplace diversity and organizational performance
  • The effectiveness of dialectical behavior therapy in treating borderline personality disorder
  • The correlation between childhood abuse and adult mental health outcomes
  • The effect of sleep deprivation on cognitive function
  • The impact of trade policies on international trade and economic growth
  • The relationship between employee engagement and organizational commitment
  • The effectiveness of cognitive therapy in treating postpartum depression
  • The correlation between family meals and child obesity rates
  • The effect of parental involvement in sports on child athletic performance
  • The impact of social entrepreneurship on sustainable development
  • The relationship between emotional labor and job burnout
  • The effectiveness of art therapy in treating dementia
  • The correlation between social media use and academic procrastination
  • The effect of poverty on childhood educational attainment
  • The impact of urban green spaces on mental health
  • The relationship between job insecurity and employee well-being
  • The effectiveness of virtual reality exposure therapy in treating anxiety disorders
  • The correlation between childhood trauma and substance abuse
  • The effect of screen time on children’s social skills
  • The impact of trade unions on employee job satisfaction
  • The relationship between cultural intelligence and cross-cultural communication
  • The effectiveness of acceptance and commitment therapy in treating chronic pain
  • The correlation between childhood obesity and adult health outcomes
  • The effect of gender diversity on corporate performance
  • The impact of environmental regulations on industry competitiveness.
  • The impact of renewable energy policies on greenhouse gas emissions
  • The relationship between workplace diversity and team performance
  • The effectiveness of group therapy in treating substance abuse
  • The correlation between parental involvement and social skills in early childhood
  • The effect of technology use on sleep patterns
  • The impact of government regulations on small business growth
  • The relationship between job satisfaction and employee turnover
  • The effectiveness of virtual reality therapy in treating anxiety disorders
  • The correlation between parental involvement and academic motivation in adolescents
  • The effect of social media on political engagement
  • The impact of urbanization on mental health
  • The relationship between corporate social responsibility and consumer trust
  • The correlation between early childhood education and social-emotional development
  • The effect of screen time on cognitive development in young children
  • The impact of trade policies on global economic growth
  • The relationship between workplace diversity and innovation
  • The effectiveness of family therapy in treating eating disorders
  • The correlation between parental involvement and college persistence
  • The effect of social media on body image and self-esteem
  • The impact of environmental regulations on business competitiveness
  • The relationship between job autonomy and job satisfaction
  • The effectiveness of virtual reality therapy in treating phobias
  • The correlation between parental involvement and academic achievement in college
  • The effect of social media on sleep quality
  • The impact of immigration policies on social integration
  • The relationship between workplace diversity and employee well-being
  • The effectiveness of psychodynamic therapy in treating personality disorders
  • The correlation between early childhood education and executive function skills
  • The effect of parental involvement on STEM education outcomes
  • The impact of trade policies on domestic employment rates
  • The relationship between job insecurity and mental health
  • The effectiveness of exposure therapy in treating PTSD
  • The correlation between parental involvement and social mobility
  • The effect of social media on intergroup relations
  • The impact of urbanization on air pollution and respiratory health.
  • The relationship between emotional intelligence and leadership effectiveness
  • The effectiveness of cognitive-behavioral therapy in treating depression
  • The correlation between early childhood education and language development
  • The effect of parental involvement on academic achievement in STEM fields
  • The impact of trade policies on income inequality
  • The relationship between workplace diversity and customer satisfaction
  • The effectiveness of mindfulness-based therapy in treating anxiety disorders
  • The correlation between parental involvement and civic engagement in adolescents
  • The effect of social media on mental health among teenagers
  • The impact of public transportation policies on traffic congestion
  • The relationship between job stress and job performance
  • The effectiveness of group therapy in treating depression
  • The correlation between early childhood education and cognitive development
  • The effect of parental involvement on academic motivation in college
  • The impact of environmental regulations on energy consumption
  • The relationship between workplace diversity and employee engagement
  • The effectiveness of art therapy in treating PTSD
  • The correlation between parental involvement and academic success in vocational education
  • The effect of social media on academic achievement in college
  • The impact of tax policies on economic growth
  • The relationship between job flexibility and work-life balance
  • The effectiveness of acceptance and commitment therapy in treating anxiety disorders
  • The correlation between early childhood education and social competence
  • The effect of parental involvement on career readiness in high school
  • The impact of immigration policies on crime rates
  • The relationship between workplace diversity and employee retention
  • The effectiveness of play therapy in treating trauma
  • The correlation between parental involvement and academic success in online learning
  • The effect of social media on body dissatisfaction among women
  • The impact of urbanization on public health infrastructure
  • The relationship between job satisfaction and job performance
  • The effectiveness of eye movement desensitization and reprocessing therapy in treating PTSD
  • The correlation between early childhood education and social skills in adolescence
  • The effect of parental involvement on academic achievement in the arts
  • The impact of trade policies on foreign investment
  • The relationship between workplace diversity and decision-making
  • The effectiveness of exposure and response prevention therapy in treating OCD
  • The correlation between parental involvement and academic success in special education
  • The impact of zoning laws on affordable housing
  • The relationship between job design and employee motivation
  • The effectiveness of cognitive rehabilitation therapy in treating traumatic brain injury
  • The correlation between early childhood education and social-emotional learning
  • The effect of parental involvement on academic achievement in foreign language learning
  • The impact of trade policies on the environment
  • The relationship between workplace diversity and creativity
  • The effectiveness of emotion-focused therapy in treating relationship problems
  • The correlation between parental involvement and academic success in music education
  • The effect of social media on interpersonal communication skills
  • The impact of public health campaigns on health behaviors
  • The relationship between job resources and job stress
  • The effectiveness of equine therapy in treating substance abuse
  • The correlation between early childhood education and self-regulation
  • The effect of parental involvement on academic achievement in physical education
  • The impact of immigration policies on cultural assimilation
  • The relationship between workplace diversity and conflict resolution
  • The effectiveness of schema therapy in treating personality disorders
  • The correlation between parental involvement and academic success in career and technical education
  • The effect of social media on trust in government institutions
  • The impact of urbanization on public transportation systems
  • The relationship between job demands and job stress
  • The correlation between early childhood education and executive functioning
  • The effect of parental involvement on academic achievement in computer science
  • The effectiveness of cognitive processing therapy in treating PTSD
  • The correlation between parental involvement and academic success in homeschooling
  • The effect of social media on cyberbullying behavior
  • The impact of urbanization on air quality
  • The effectiveness of dance therapy in treating anxiety disorders
  • The correlation between early childhood education and math achievement
  • The effect of parental involvement on academic achievement in health education
  • The impact of global warming on agriculture
  • The effectiveness of narrative therapy in treating depression
  • The correlation between parental involvement and academic success in character education
  • The effect of social media on political participation
  • The impact of technology on job displacement
  • The relationship between job resources and job satisfaction
  • The effectiveness of art therapy in treating addiction
  • The correlation between early childhood education and reading comprehension
  • The effect of parental involvement on academic achievement in environmental education
  • The impact of income inequality on social mobility
  • The relationship between workplace diversity and organizational culture
  • The effectiveness of solution-focused brief therapy in treating anxiety disorders
  • The correlation between parental involvement and academic success in physical therapy education
  • The effect of social media on misinformation
  • The impact of green energy policies on economic growth
  • The relationship between job demands and employee well-being
  • The correlation between early childhood education and science achievement
  • The effect of parental involvement on academic achievement in religious education
  • The impact of gender diversity on corporate governance
  • The relationship between workplace diversity and ethical decision-making
  • The correlation between parental involvement and academic success in dental hygiene education
  • The effect of social media on self-esteem among adolescents
  • The impact of renewable energy policies on energy security
  • The effect of parental involvement on academic achievement in social studies
  • The impact of trade policies on job growth
  • The relationship between workplace diversity and leadership styles
  • The correlation between parental involvement and academic success in online vocational training
  • The effect of social media on self-esteem among men
  • The impact of urbanization on air pollution levels
  • The effectiveness of music therapy in treating depression
  • The correlation between early childhood education and math skills
  • The effect of parental involvement on academic achievement in language arts
  • The impact of immigration policies on labor market outcomes
  • The effectiveness of hypnotherapy in treating phobias
  • The effect of social media on political engagement among young adults
  • The impact of urbanization on access to green spaces
  • The relationship between job crafting and job satisfaction
  • The effectiveness of exposure therapy in treating specific phobias
  • The correlation between early childhood education and spatial reasoning
  • The effect of parental involvement on academic achievement in business education
  • The impact of trade policies on economic inequality
  • The effectiveness of narrative therapy in treating PTSD
  • The correlation between parental involvement and academic success in nursing education
  • The effect of social media on sleep quality among adolescents
  • The impact of urbanization on crime rates
  • The relationship between job insecurity and turnover intentions
  • The effectiveness of pet therapy in treating anxiety disorders
  • The correlation between early childhood education and STEM skills
  • The effect of parental involvement on academic achievement in culinary education
  • The impact of immigration policies on housing affordability
  • The relationship between workplace diversity and employee satisfaction
  • The effectiveness of mindfulness-based stress reduction in treating chronic pain
  • The correlation between parental involvement and academic success in art education
  • The effect of social media on academic procrastination among college students
  • The impact of urbanization on public safety services.

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A Practical Guide to Writing Quantitative and Qualitative Research Questions and Hypotheses in Scholarly Articles

Edward barroga.

1 Department of General Education, Graduate School of Nursing Science, St. Luke’s International University, Tokyo, Japan.

Glafera Janet Matanguihan

2 Department of Biological Sciences, Messiah University, Mechanicsburg, PA, USA.

The development of research questions and the subsequent hypotheses are prerequisites to defining the main research purpose and specific objectives of a study. Consequently, these objectives determine the study design and research outcome. The development of research questions is a process based on knowledge of current trends, cutting-edge studies, and technological advances in the research field. Excellent research questions are focused and require a comprehensive literature search and in-depth understanding of the problem being investigated. Initially, research questions may be written as descriptive questions which could be developed into inferential questions. These questions must be specific and concise to provide a clear foundation for developing hypotheses. Hypotheses are more formal predictions about the research outcomes. These specify the possible results that may or may not be expected regarding the relationship between groups. Thus, research questions and hypotheses clarify the main purpose and specific objectives of the study, which in turn dictate the design of the study, its direction, and outcome. Studies developed from good research questions and hypotheses will have trustworthy outcomes with wide-ranging social and health implications.

INTRODUCTION

Scientific research is usually initiated by posing evidenced-based research questions which are then explicitly restated as hypotheses. 1 , 2 The hypotheses provide directions to guide the study, solutions, explanations, and expected results. 3 , 4 Both research questions and hypotheses are essentially formulated based on conventional theories and real-world processes, which allow the inception of novel studies and the ethical testing of ideas. 5 , 6

It is crucial to have knowledge of both quantitative and qualitative research 2 as both types of research involve writing research questions and hypotheses. 7 However, these crucial elements of research are sometimes overlooked; if not overlooked, then framed without the forethought and meticulous attention it needs. Planning and careful consideration are needed when developing quantitative or qualitative research, particularly when conceptualizing research questions and hypotheses. 4

There is a continuing need to support researchers in the creation of innovative research questions and hypotheses, as well as for journal articles that carefully review these elements. 1 When research questions and hypotheses are not carefully thought of, unethical studies and poor outcomes usually ensue. Carefully formulated research questions and hypotheses define well-founded objectives, which in turn determine the appropriate design, course, and outcome of the study. This article then aims to discuss in detail the various aspects of crafting research questions and hypotheses, with the goal of guiding researchers as they develop their own. Examples from the authors and peer-reviewed scientific articles in the healthcare field are provided to illustrate key points.

DEFINITIONS AND RELATIONSHIP OF RESEARCH QUESTIONS AND HYPOTHESES

A research question is what a study aims to answer after data analysis and interpretation. The answer is written in length in the discussion section of the paper. Thus, the research question gives a preview of the different parts and variables of the study meant to address the problem posed in the research question. 1 An excellent research question clarifies the research writing while facilitating understanding of the research topic, objective, scope, and limitations of the study. 5

On the other hand, a research hypothesis is an educated statement of an expected outcome. This statement is based on background research and current knowledge. 8 , 9 The research hypothesis makes a specific prediction about a new phenomenon 10 or a formal statement on the expected relationship between an independent variable and a dependent variable. 3 , 11 It provides a tentative answer to the research question to be tested or explored. 4

Hypotheses employ reasoning to predict a theory-based outcome. 10 These can also be developed from theories by focusing on components of theories that have not yet been observed. 10 The validity of hypotheses is often based on the testability of the prediction made in a reproducible experiment. 8

Conversely, hypotheses can also be rephrased as research questions. Several hypotheses based on existing theories and knowledge may be needed to answer a research question. Developing ethical research questions and hypotheses creates a research design that has logical relationships among variables. These relationships serve as a solid foundation for the conduct of the study. 4 , 11 Haphazardly constructed research questions can result in poorly formulated hypotheses and improper study designs, leading to unreliable results. Thus, the formulations of relevant research questions and verifiable hypotheses are crucial when beginning research. 12

CHARACTERISTICS OF GOOD RESEARCH QUESTIONS AND HYPOTHESES

Excellent research questions are specific and focused. These integrate collective data and observations to confirm or refute the subsequent hypotheses. Well-constructed hypotheses are based on previous reports and verify the research context. These are realistic, in-depth, sufficiently complex, and reproducible. More importantly, these hypotheses can be addressed and tested. 13

There are several characteristics of well-developed hypotheses. Good hypotheses are 1) empirically testable 7 , 10 , 11 , 13 ; 2) backed by preliminary evidence 9 ; 3) testable by ethical research 7 , 9 ; 4) based on original ideas 9 ; 5) have evidenced-based logical reasoning 10 ; and 6) can be predicted. 11 Good hypotheses can infer ethical and positive implications, indicating the presence of a relationship or effect relevant to the research theme. 7 , 11 These are initially developed from a general theory and branch into specific hypotheses by deductive reasoning. In the absence of a theory to base the hypotheses, inductive reasoning based on specific observations or findings form more general hypotheses. 10

TYPES OF RESEARCH QUESTIONS AND HYPOTHESES

Research questions and hypotheses are developed according to the type of research, which can be broadly classified into quantitative and qualitative research. We provide a summary of the types of research questions and hypotheses under quantitative and qualitative research categories in Table 1 .

Quantitative research questionsQuantitative research hypotheses
Descriptive research questionsSimple hypothesis
Comparative research questionsComplex hypothesis
Relationship research questionsDirectional hypothesis
Non-directional hypothesis
Associative hypothesis
Causal hypothesis
Null hypothesis
Alternative hypothesis
Working hypothesis
Statistical hypothesis
Logical hypothesis
Hypothesis-testing
Qualitative research questionsQualitative research hypotheses
Contextual research questionsHypothesis-generating
Descriptive research questions
Evaluation research questions
Explanatory research questions
Exploratory research questions
Generative research questions
Ideological research questions
Ethnographic research questions
Phenomenological research questions
Grounded theory questions
Qualitative case study questions

Research questions in quantitative research

In quantitative research, research questions inquire about the relationships among variables being investigated and are usually framed at the start of the study. These are precise and typically linked to the subject population, dependent and independent variables, and research design. 1 Research questions may also attempt to describe the behavior of a population in relation to one or more variables, or describe the characteristics of variables to be measured ( descriptive research questions ). 1 , 5 , 14 These questions may also aim to discover differences between groups within the context of an outcome variable ( comparative research questions ), 1 , 5 , 14 or elucidate trends and interactions among variables ( relationship research questions ). 1 , 5 We provide examples of descriptive, comparative, and relationship research questions in quantitative research in Table 2 .

Quantitative research questions
Descriptive research question
- Measures responses of subjects to variables
- Presents variables to measure, analyze, or assess
What is the proportion of resident doctors in the hospital who have mastered ultrasonography (response of subjects to a variable) as a diagnostic technique in their clinical training?
Comparative research question
- Clarifies difference between one group with outcome variable and another group without outcome variable
Is there a difference in the reduction of lung metastasis in osteosarcoma patients who received the vitamin D adjunctive therapy (group with outcome variable) compared with osteosarcoma patients who did not receive the vitamin D adjunctive therapy (group without outcome variable)?
- Compares the effects of variables
How does the vitamin D analogue 22-Oxacalcitriol (variable 1) mimic the antiproliferative activity of 1,25-Dihydroxyvitamin D (variable 2) in osteosarcoma cells?
Relationship research question
- Defines trends, association, relationships, or interactions between dependent variable and independent variable
Is there a relationship between the number of medical student suicide (dependent variable) and the level of medical student stress (independent variable) in Japan during the first wave of the COVID-19 pandemic?

Hypotheses in quantitative research

In quantitative research, hypotheses predict the expected relationships among variables. 15 Relationships among variables that can be predicted include 1) between a single dependent variable and a single independent variable ( simple hypothesis ) or 2) between two or more independent and dependent variables ( complex hypothesis ). 4 , 11 Hypotheses may also specify the expected direction to be followed and imply an intellectual commitment to a particular outcome ( directional hypothesis ) 4 . On the other hand, hypotheses may not predict the exact direction and are used in the absence of a theory, or when findings contradict previous studies ( non-directional hypothesis ). 4 In addition, hypotheses can 1) define interdependency between variables ( associative hypothesis ), 4 2) propose an effect on the dependent variable from manipulation of the independent variable ( causal hypothesis ), 4 3) state a negative relationship between two variables ( null hypothesis ), 4 , 11 , 15 4) replace the working hypothesis if rejected ( alternative hypothesis ), 15 explain the relationship of phenomena to possibly generate a theory ( working hypothesis ), 11 5) involve quantifiable variables that can be tested statistically ( statistical hypothesis ), 11 6) or express a relationship whose interlinks can be verified logically ( logical hypothesis ). 11 We provide examples of simple, complex, directional, non-directional, associative, causal, null, alternative, working, statistical, and logical hypotheses in quantitative research, as well as the definition of quantitative hypothesis-testing research in Table 3 .

Quantitative research hypotheses
Simple hypothesis
- Predicts relationship between single dependent variable and single independent variable
If the dose of the new medication (single independent variable) is high, blood pressure (single dependent variable) is lowered.
Complex hypothesis
- Foretells relationship between two or more independent and dependent variables
The higher the use of anticancer drugs, radiation therapy, and adjunctive agents (3 independent variables), the higher would be the survival rate (1 dependent variable).
Directional hypothesis
- Identifies study direction based on theory towards particular outcome to clarify relationship between variables
Privately funded research projects will have a larger international scope (study direction) than publicly funded research projects.
Non-directional hypothesis
- Nature of relationship between two variables or exact study direction is not identified
- Does not involve a theory
Women and men are different in terms of helpfulness. (Exact study direction is not identified)
Associative hypothesis
- Describes variable interdependency
- Change in one variable causes change in another variable
A larger number of people vaccinated against COVID-19 in the region (change in independent variable) will reduce the region’s incidence of COVID-19 infection (change in dependent variable).
Causal hypothesis
- An effect on dependent variable is predicted from manipulation of independent variable
A change into a high-fiber diet (independent variable) will reduce the blood sugar level (dependent variable) of the patient.
Null hypothesis
- A negative statement indicating no relationship or difference between 2 variables
There is no significant difference in the severity of pulmonary metastases between the new drug (variable 1) and the current drug (variable 2).
Alternative hypothesis
- Following a null hypothesis, an alternative hypothesis predicts a relationship between 2 study variables
The new drug (variable 1) is better on average in reducing the level of pain from pulmonary metastasis than the current drug (variable 2).
Working hypothesis
- A hypothesis that is initially accepted for further research to produce a feasible theory
Dairy cows fed with concentrates of different formulations will produce different amounts of milk.
Statistical hypothesis
- Assumption about the value of population parameter or relationship among several population characteristics
- Validity tested by a statistical experiment or analysis
The mean recovery rate from COVID-19 infection (value of population parameter) is not significantly different between population 1 and population 2.
There is a positive correlation between the level of stress at the workplace and the number of suicides (population characteristics) among working people in Japan.
Logical hypothesis
- Offers or proposes an explanation with limited or no extensive evidence
If healthcare workers provide more educational programs about contraception methods, the number of adolescent pregnancies will be less.
Hypothesis-testing (Quantitative hypothesis-testing research)
- Quantitative research uses deductive reasoning.
- This involves the formation of a hypothesis, collection of data in the investigation of the problem, analysis and use of the data from the investigation, and drawing of conclusions to validate or nullify the hypotheses.

Research questions in qualitative research

Unlike research questions in quantitative research, research questions in qualitative research are usually continuously reviewed and reformulated. The central question and associated subquestions are stated more than the hypotheses. 15 The central question broadly explores a complex set of factors surrounding the central phenomenon, aiming to present the varied perspectives of participants. 15

There are varied goals for which qualitative research questions are developed. These questions can function in several ways, such as to 1) identify and describe existing conditions ( contextual research question s); 2) describe a phenomenon ( descriptive research questions ); 3) assess the effectiveness of existing methods, protocols, theories, or procedures ( evaluation research questions ); 4) examine a phenomenon or analyze the reasons or relationships between subjects or phenomena ( explanatory research questions ); or 5) focus on unknown aspects of a particular topic ( exploratory research questions ). 5 In addition, some qualitative research questions provide new ideas for the development of theories and actions ( generative research questions ) or advance specific ideologies of a position ( ideological research questions ). 1 Other qualitative research questions may build on a body of existing literature and become working guidelines ( ethnographic research questions ). Research questions may also be broadly stated without specific reference to the existing literature or a typology of questions ( phenomenological research questions ), may be directed towards generating a theory of some process ( grounded theory questions ), or may address a description of the case and the emerging themes ( qualitative case study questions ). 15 We provide examples of contextual, descriptive, evaluation, explanatory, exploratory, generative, ideological, ethnographic, phenomenological, grounded theory, and qualitative case study research questions in qualitative research in Table 4 , and the definition of qualitative hypothesis-generating research in Table 5 .

Qualitative research questions
Contextual research question
- Ask the nature of what already exists
- Individuals or groups function to further clarify and understand the natural context of real-world problems
What are the experiences of nurses working night shifts in healthcare during the COVID-19 pandemic? (natural context of real-world problems)
Descriptive research question
- Aims to describe a phenomenon
What are the different forms of disrespect and abuse (phenomenon) experienced by Tanzanian women when giving birth in healthcare facilities?
Evaluation research question
- Examines the effectiveness of existing practice or accepted frameworks
How effective are decision aids (effectiveness of existing practice) in helping decide whether to give birth at home or in a healthcare facility?
Explanatory research question
- Clarifies a previously studied phenomenon and explains why it occurs
Why is there an increase in teenage pregnancy (phenomenon) in Tanzania?
Exploratory research question
- Explores areas that have not been fully investigated to have a deeper understanding of the research problem
What factors affect the mental health of medical students (areas that have not yet been fully investigated) during the COVID-19 pandemic?
Generative research question
- Develops an in-depth understanding of people’s behavior by asking ‘how would’ or ‘what if’ to identify problems and find solutions
How would the extensive research experience of the behavior of new staff impact the success of the novel drug initiative?
Ideological research question
- Aims to advance specific ideas or ideologies of a position
Are Japanese nurses who volunteer in remote African hospitals able to promote humanized care of patients (specific ideas or ideologies) in the areas of safe patient environment, respect of patient privacy, and provision of accurate information related to health and care?
Ethnographic research question
- Clarifies peoples’ nature, activities, their interactions, and the outcomes of their actions in specific settings
What are the demographic characteristics, rehabilitative treatments, community interactions, and disease outcomes (nature, activities, their interactions, and the outcomes) of people in China who are suffering from pneumoconiosis?
Phenomenological research question
- Knows more about the phenomena that have impacted an individual
What are the lived experiences of parents who have been living with and caring for children with a diagnosis of autism? (phenomena that have impacted an individual)
Grounded theory question
- Focuses on social processes asking about what happens and how people interact, or uncovering social relationships and behaviors of groups
What are the problems that pregnant adolescents face in terms of social and cultural norms (social processes), and how can these be addressed?
Qualitative case study question
- Assesses a phenomenon using different sources of data to answer “why” and “how” questions
- Considers how the phenomenon is influenced by its contextual situation.
How does quitting work and assuming the role of a full-time mother (phenomenon assessed) change the lives of women in Japan?
Qualitative research hypotheses
Hypothesis-generating (Qualitative hypothesis-generating research)
- Qualitative research uses inductive reasoning.
- This involves data collection from study participants or the literature regarding a phenomenon of interest, using the collected data to develop a formal hypothesis, and using the formal hypothesis as a framework for testing the hypothesis.
- Qualitative exploratory studies explore areas deeper, clarifying subjective experience and allowing formulation of a formal hypothesis potentially testable in a future quantitative approach.

Qualitative studies usually pose at least one central research question and several subquestions starting with How or What . These research questions use exploratory verbs such as explore or describe . These also focus on one central phenomenon of interest, and may mention the participants and research site. 15

Hypotheses in qualitative research

Hypotheses in qualitative research are stated in the form of a clear statement concerning the problem to be investigated. Unlike in quantitative research where hypotheses are usually developed to be tested, qualitative research can lead to both hypothesis-testing and hypothesis-generating outcomes. 2 When studies require both quantitative and qualitative research questions, this suggests an integrative process between both research methods wherein a single mixed-methods research question can be developed. 1

FRAMEWORKS FOR DEVELOPING RESEARCH QUESTIONS AND HYPOTHESES

Research questions followed by hypotheses should be developed before the start of the study. 1 , 12 , 14 It is crucial to develop feasible research questions on a topic that is interesting to both the researcher and the scientific community. This can be achieved by a meticulous review of previous and current studies to establish a novel topic. Specific areas are subsequently focused on to generate ethical research questions. The relevance of the research questions is evaluated in terms of clarity of the resulting data, specificity of the methodology, objectivity of the outcome, depth of the research, and impact of the study. 1 , 5 These aspects constitute the FINER criteria (i.e., Feasible, Interesting, Novel, Ethical, and Relevant). 1 Clarity and effectiveness are achieved if research questions meet the FINER criteria. In addition to the FINER criteria, Ratan et al. described focus, complexity, novelty, feasibility, and measurability for evaluating the effectiveness of research questions. 14

The PICOT and PEO frameworks are also used when developing research questions. 1 The following elements are addressed in these frameworks, PICOT: P-population/patients/problem, I-intervention or indicator being studied, C-comparison group, O-outcome of interest, and T-timeframe of the study; PEO: P-population being studied, E-exposure to preexisting conditions, and O-outcome of interest. 1 Research questions are also considered good if these meet the “FINERMAPS” framework: Feasible, Interesting, Novel, Ethical, Relevant, Manageable, Appropriate, Potential value/publishable, and Systematic. 14

As we indicated earlier, research questions and hypotheses that are not carefully formulated result in unethical studies or poor outcomes. To illustrate this, we provide some examples of ambiguous research question and hypotheses that result in unclear and weak research objectives in quantitative research ( Table 6 ) 16 and qualitative research ( Table 7 ) 17 , and how to transform these ambiguous research question(s) and hypothesis(es) into clear and good statements.

VariablesUnclear and weak statement (Statement 1) Clear and good statement (Statement 2) Points to avoid
Research questionWhich is more effective between smoke moxibustion and smokeless moxibustion?“Moreover, regarding smoke moxibustion versus smokeless moxibustion, it remains unclear which is more effective, safe, and acceptable to pregnant women, and whether there is any difference in the amount of heat generated.” 1) Vague and unfocused questions
2) Closed questions simply answerable by yes or no
3) Questions requiring a simple choice
HypothesisThe smoke moxibustion group will have higher cephalic presentation.“Hypothesis 1. The smoke moxibustion stick group (SM group) and smokeless moxibustion stick group (-SLM group) will have higher rates of cephalic presentation after treatment than the control group.1) Unverifiable hypotheses
Hypothesis 2. The SM group and SLM group will have higher rates of cephalic presentation at birth than the control group.2) Incompletely stated groups of comparison
Hypothesis 3. There will be no significant differences in the well-being of the mother and child among the three groups in terms of the following outcomes: premature birth, premature rupture of membranes (PROM) at < 37 weeks, Apgar score < 7 at 5 min, umbilical cord blood pH < 7.1, admission to neonatal intensive care unit (NICU), and intrauterine fetal death.” 3) Insufficiently described variables or outcomes
Research objectiveTo determine which is more effective between smoke moxibustion and smokeless moxibustion.“The specific aims of this pilot study were (a) to compare the effects of smoke moxibustion and smokeless moxibustion treatments with the control group as a possible supplement to ECV for converting breech presentation to cephalic presentation and increasing adherence to the newly obtained cephalic position, and (b) to assess the effects of these treatments on the well-being of the mother and child.” 1) Poor understanding of the research question and hypotheses
2) Insufficient description of population, variables, or study outcomes

a These statements were composed for comparison and illustrative purposes only.

b These statements are direct quotes from Higashihara and Horiuchi. 16

VariablesUnclear and weak statement (Statement 1)Clear and good statement (Statement 2)Points to avoid
Research questionDoes disrespect and abuse (D&A) occur in childbirth in Tanzania?How does disrespect and abuse (D&A) occur and what are the types of physical and psychological abuses observed in midwives’ actual care during facility-based childbirth in urban Tanzania?1) Ambiguous or oversimplistic questions
2) Questions unverifiable by data collection and analysis
HypothesisDisrespect and abuse (D&A) occur in childbirth in Tanzania.Hypothesis 1: Several types of physical and psychological abuse by midwives in actual care occur during facility-based childbirth in urban Tanzania.1) Statements simply expressing facts
Hypothesis 2: Weak nursing and midwifery management contribute to the D&A of women during facility-based childbirth in urban Tanzania.2) Insufficiently described concepts or variables
Research objectiveTo describe disrespect and abuse (D&A) in childbirth in Tanzania.“This study aimed to describe from actual observations the respectful and disrespectful care received by women from midwives during their labor period in two hospitals in urban Tanzania.” 1) Statements unrelated to the research question and hypotheses
2) Unattainable or unexplorable objectives

a This statement is a direct quote from Shimoda et al. 17

The other statements were composed for comparison and illustrative purposes only.

CONSTRUCTING RESEARCH QUESTIONS AND HYPOTHESES

To construct effective research questions and hypotheses, it is very important to 1) clarify the background and 2) identify the research problem at the outset of the research, within a specific timeframe. 9 Then, 3) review or conduct preliminary research to collect all available knowledge about the possible research questions by studying theories and previous studies. 18 Afterwards, 4) construct research questions to investigate the research problem. Identify variables to be accessed from the research questions 4 and make operational definitions of constructs from the research problem and questions. Thereafter, 5) construct specific deductive or inductive predictions in the form of hypotheses. 4 Finally, 6) state the study aims . This general flow for constructing effective research questions and hypotheses prior to conducting research is shown in Fig. 1 .

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Research questions are used more frequently in qualitative research than objectives or hypotheses. 3 These questions seek to discover, understand, explore or describe experiences by asking “What” or “How.” The questions are open-ended to elicit a description rather than to relate variables or compare groups. The questions are continually reviewed, reformulated, and changed during the qualitative study. 3 Research questions are also used more frequently in survey projects than hypotheses in experiments in quantitative research to compare variables and their relationships.

Hypotheses are constructed based on the variables identified and as an if-then statement, following the template, ‘If a specific action is taken, then a certain outcome is expected.’ At this stage, some ideas regarding expectations from the research to be conducted must be drawn. 18 Then, the variables to be manipulated (independent) and influenced (dependent) are defined. 4 Thereafter, the hypothesis is stated and refined, and reproducible data tailored to the hypothesis are identified, collected, and analyzed. 4 The hypotheses must be testable and specific, 18 and should describe the variables and their relationships, the specific group being studied, and the predicted research outcome. 18 Hypotheses construction involves a testable proposition to be deduced from theory, and independent and dependent variables to be separated and measured separately. 3 Therefore, good hypotheses must be based on good research questions constructed at the start of a study or trial. 12

In summary, research questions are constructed after establishing the background of the study. Hypotheses are then developed based on the research questions. Thus, it is crucial to have excellent research questions to generate superior hypotheses. In turn, these would determine the research objectives and the design of the study, and ultimately, the outcome of the research. 12 Algorithms for building research questions and hypotheses are shown in Fig. 2 for quantitative research and in Fig. 3 for qualitative research.

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EXAMPLES OF RESEARCH QUESTIONS FROM PUBLISHED ARTICLES

  • EXAMPLE 1. Descriptive research question (quantitative research)
  • - Presents research variables to be assessed (distinct phenotypes and subphenotypes)
  • “BACKGROUND: Since COVID-19 was identified, its clinical and biological heterogeneity has been recognized. Identifying COVID-19 phenotypes might help guide basic, clinical, and translational research efforts.
  • RESEARCH QUESTION: Does the clinical spectrum of patients with COVID-19 contain distinct phenotypes and subphenotypes? ” 19
  • EXAMPLE 2. Relationship research question (quantitative research)
  • - Shows interactions between dependent variable (static postural control) and independent variable (peripheral visual field loss)
  • “Background: Integration of visual, vestibular, and proprioceptive sensations contributes to postural control. People with peripheral visual field loss have serious postural instability. However, the directional specificity of postural stability and sensory reweighting caused by gradual peripheral visual field loss remain unclear.
  • Research question: What are the effects of peripheral visual field loss on static postural control ?” 20
  • EXAMPLE 3. Comparative research question (quantitative research)
  • - Clarifies the difference among groups with an outcome variable (patients enrolled in COMPERA with moderate PH or severe PH in COPD) and another group without the outcome variable (patients with idiopathic pulmonary arterial hypertension (IPAH))
  • “BACKGROUND: Pulmonary hypertension (PH) in COPD is a poorly investigated clinical condition.
  • RESEARCH QUESTION: Which factors determine the outcome of PH in COPD?
  • STUDY DESIGN AND METHODS: We analyzed the characteristics and outcome of patients enrolled in the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA) with moderate or severe PH in COPD as defined during the 6th PH World Symposium who received medical therapy for PH and compared them with patients with idiopathic pulmonary arterial hypertension (IPAH) .” 21
  • EXAMPLE 4. Exploratory research question (qualitative research)
  • - Explores areas that have not been fully investigated (perspectives of families and children who receive care in clinic-based child obesity treatment) to have a deeper understanding of the research problem
  • “Problem: Interventions for children with obesity lead to only modest improvements in BMI and long-term outcomes, and data are limited on the perspectives of families of children with obesity in clinic-based treatment. This scoping review seeks to answer the question: What is known about the perspectives of families and children who receive care in clinic-based child obesity treatment? This review aims to explore the scope of perspectives reported by families of children with obesity who have received individualized outpatient clinic-based obesity treatment.” 22
  • EXAMPLE 5. Relationship research question (quantitative research)
  • - Defines interactions between dependent variable (use of ankle strategies) and independent variable (changes in muscle tone)
  • “Background: To maintain an upright standing posture against external disturbances, the human body mainly employs two types of postural control strategies: “ankle strategy” and “hip strategy.” While it has been reported that the magnitude of the disturbance alters the use of postural control strategies, it has not been elucidated how the level of muscle tone, one of the crucial parameters of bodily function, determines the use of each strategy. We have previously confirmed using forward dynamics simulations of human musculoskeletal models that an increased muscle tone promotes the use of ankle strategies. The objective of the present study was to experimentally evaluate a hypothesis: an increased muscle tone promotes the use of ankle strategies. Research question: Do changes in the muscle tone affect the use of ankle strategies ?” 23

EXAMPLES OF HYPOTHESES IN PUBLISHED ARTICLES

  • EXAMPLE 1. Working hypothesis (quantitative research)
  • - A hypothesis that is initially accepted for further research to produce a feasible theory
  • “As fever may have benefit in shortening the duration of viral illness, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response when taken during the early stages of COVID-19 illness .” 24
  • “In conclusion, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response . The difference in perceived safety of these agents in COVID-19 illness could be related to the more potent efficacy to reduce fever with ibuprofen compared to acetaminophen. Compelling data on the benefit of fever warrant further research and review to determine when to treat or withhold ibuprofen for early stage fever for COVID-19 and other related viral illnesses .” 24
  • EXAMPLE 2. Exploratory hypothesis (qualitative research)
  • - Explores particular areas deeper to clarify subjective experience and develop a formal hypothesis potentially testable in a future quantitative approach
  • “We hypothesized that when thinking about a past experience of help-seeking, a self distancing prompt would cause increased help-seeking intentions and more favorable help-seeking outcome expectations .” 25
  • “Conclusion
  • Although a priori hypotheses were not supported, further research is warranted as results indicate the potential for using self-distancing approaches to increasing help-seeking among some people with depressive symptomatology.” 25
  • EXAMPLE 3. Hypothesis-generating research to establish a framework for hypothesis testing (qualitative research)
  • “We hypothesize that compassionate care is beneficial for patients (better outcomes), healthcare systems and payers (lower costs), and healthcare providers (lower burnout). ” 26
  • Compassionomics is the branch of knowledge and scientific study of the effects of compassionate healthcare. Our main hypotheses are that compassionate healthcare is beneficial for (1) patients, by improving clinical outcomes, (2) healthcare systems and payers, by supporting financial sustainability, and (3) HCPs, by lowering burnout and promoting resilience and well-being. The purpose of this paper is to establish a scientific framework for testing the hypotheses above . If these hypotheses are confirmed through rigorous research, compassionomics will belong in the science of evidence-based medicine, with major implications for all healthcare domains.” 26
  • EXAMPLE 4. Statistical hypothesis (quantitative research)
  • - An assumption is made about the relationship among several population characteristics ( gender differences in sociodemographic and clinical characteristics of adults with ADHD ). Validity is tested by statistical experiment or analysis ( chi-square test, Students t-test, and logistic regression analysis)
  • “Our research investigated gender differences in sociodemographic and clinical characteristics of adults with ADHD in a Japanese clinical sample. Due to unique Japanese cultural ideals and expectations of women's behavior that are in opposition to ADHD symptoms, we hypothesized that women with ADHD experience more difficulties and present more dysfunctions than men . We tested the following hypotheses: first, women with ADHD have more comorbidities than men with ADHD; second, women with ADHD experience more social hardships than men, such as having less full-time employment and being more likely to be divorced.” 27
  • “Statistical Analysis
  • ( text omitted ) Between-gender comparisons were made using the chi-squared test for categorical variables and Students t-test for continuous variables…( text omitted ). A logistic regression analysis was performed for employment status, marital status, and comorbidity to evaluate the independent effects of gender on these dependent variables.” 27

EXAMPLES OF HYPOTHESIS AS WRITTEN IN PUBLISHED ARTICLES IN RELATION TO OTHER PARTS

  • EXAMPLE 1. Background, hypotheses, and aims are provided
  • “Pregnant women need skilled care during pregnancy and childbirth, but that skilled care is often delayed in some countries …( text omitted ). The focused antenatal care (FANC) model of WHO recommends that nurses provide information or counseling to all pregnant women …( text omitted ). Job aids are visual support materials that provide the right kind of information using graphics and words in a simple and yet effective manner. When nurses are not highly trained or have many work details to attend to, these job aids can serve as a content reminder for the nurses and can be used for educating their patients (Jennings, Yebadokpo, Affo, & Agbogbe, 2010) ( text omitted ). Importantly, additional evidence is needed to confirm how job aids can further improve the quality of ANC counseling by health workers in maternal care …( text omitted )” 28
  • “ This has led us to hypothesize that the quality of ANC counseling would be better if supported by job aids. Consequently, a better quality of ANC counseling is expected to produce higher levels of awareness concerning the danger signs of pregnancy and a more favorable impression of the caring behavior of nurses .” 28
  • “This study aimed to examine the differences in the responses of pregnant women to a job aid-supported intervention during ANC visit in terms of 1) their understanding of the danger signs of pregnancy and 2) their impression of the caring behaviors of nurses to pregnant women in rural Tanzania.” 28
  • EXAMPLE 2. Background, hypotheses, and aims are provided
  • “We conducted a two-arm randomized controlled trial (RCT) to evaluate and compare changes in salivary cortisol and oxytocin levels of first-time pregnant women between experimental and control groups. The women in the experimental group touched and held an infant for 30 min (experimental intervention protocol), whereas those in the control group watched a DVD movie of an infant (control intervention protocol). The primary outcome was salivary cortisol level and the secondary outcome was salivary oxytocin level.” 29
  • “ We hypothesize that at 30 min after touching and holding an infant, the salivary cortisol level will significantly decrease and the salivary oxytocin level will increase in the experimental group compared with the control group .” 29
  • EXAMPLE 3. Background, aim, and hypothesis are provided
  • “In countries where the maternal mortality ratio remains high, antenatal education to increase Birth Preparedness and Complication Readiness (BPCR) is considered one of the top priorities [1]. BPCR includes birth plans during the antenatal period, such as the birthplace, birth attendant, transportation, health facility for complications, expenses, and birth materials, as well as family coordination to achieve such birth plans. In Tanzania, although increasing, only about half of all pregnant women attend an antenatal clinic more than four times [4]. Moreover, the information provided during antenatal care (ANC) is insufficient. In the resource-poor settings, antenatal group education is a potential approach because of the limited time for individual counseling at antenatal clinics.” 30
  • “This study aimed to evaluate an antenatal group education program among pregnant women and their families with respect to birth-preparedness and maternal and infant outcomes in rural villages of Tanzania.” 30
  • “ The study hypothesis was if Tanzanian pregnant women and their families received a family-oriented antenatal group education, they would (1) have a higher level of BPCR, (2) attend antenatal clinic four or more times, (3) give birth in a health facility, (4) have less complications of women at birth, and (5) have less complications and deaths of infants than those who did not receive the education .” 30

Research questions and hypotheses are crucial components to any type of research, whether quantitative or qualitative. These questions should be developed at the very beginning of the study. Excellent research questions lead to superior hypotheses, which, like a compass, set the direction of research, and can often determine the successful conduct of the study. Many research studies have floundered because the development of research questions and subsequent hypotheses was not given the thought and meticulous attention needed. The development of research questions and hypotheses is an iterative process based on extensive knowledge of the literature and insightful grasp of the knowledge gap. Focused, concise, and specific research questions provide a strong foundation for constructing hypotheses which serve as formal predictions about the research outcomes. Research questions and hypotheses are crucial elements of research that should not be overlooked. They should be carefully thought of and constructed when planning research. This avoids unethical studies and poor outcomes by defining well-founded objectives that determine the design, course, and outcome of the study.

Disclosure: The authors have no potential conflicts of interest to disclose.

Author Contributions:

  • Conceptualization: Barroga E, Matanguihan GJ.
  • Methodology: Barroga E, Matanguihan GJ.
  • Writing - original draft: Barroga E, Matanguihan GJ.
  • Writing - review & editing: Barroga E, Matanguihan GJ.

Writing Quantitative Research Studies

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  • Ankur Singh 2 ,
  • Adyya Gupta 3 &
  • Karen G. Peres 4  

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Summarizing quantitative data and its effective presentation and discussion can be challenging for students and researchers. This chapter provides a framework for adequately reporting findings from quantitative analysis in a research study for those contemplating to write a research paper. The rationale underpinning the reporting methods to maintain the credibility and integrity of quantitative studies is outlined. Commonly used terminologies in empirical studies are defined and discussed with suitable examples. Key elements that build consistency between different sections (background, methods, results, and the discussion) of a research study using quantitative methods in a journal article are explicated. Specifically, recommended standard guidelines for randomized controlled trials and observational studies for reporting and discussion of findings from quantitative studies are elaborated. Key aspects of methodology that include describing the study population, sampling strategy, data collection methods, measurements/variables, and statistical analysis which informs the quality of a study from the reviewer’s perspective are described. Effective use of references in the methods section to strengthen the rationale behind specific statistical techniques and choice of measures has been highlighted with examples. Identifying ways in which data can be most succinctly and effectively summarized in tables and graphs according to their suitability and purpose of information is also detailed in this chapter. Strategies to present and discuss the quantitative findings in a structured discussion section are also provided. Overall, the chapter provides the readers with a comprehensive set of tools to identify key strategies to be considered when reporting quantitative research.

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Case Study 3: Application of Quantitative Methodology

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Ankur Singh

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Singh, A., Gupta, A., Peres, K.G. (2019). Writing Quantitative Research Studies. In: Liamputtong, P. (eds) Handbook of Research Methods in Health Social Sciences. Springer, Singapore. https://doi.org/10.1007/978-981-10-5251-4_117

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  • 10 Research Question Examples to Guide Your Research Project

10 Research Question Examples to Guide your Research Project

Published on October 30, 2022 by Shona McCombes . Revised on October 19, 2023.

The research question is one of the most important parts of your research paper , thesis or dissertation . It’s important to spend some time assessing and refining your question before you get started.

The exact form of your question will depend on a few things, such as the length of your project, the type of research you’re conducting, the topic , and the research problem . However, all research questions should be focused, specific, and relevant to a timely social or scholarly issue.

Once you’ve read our guide on how to write a research question , you can use these examples to craft your own.

Research question Explanation
The first question is not enough. The second question is more , using .
Starting with “why” often means that your question is not enough: there are too many possible answers. By targeting just one aspect of the problem, the second question offers a clear path for research.
The first question is too broad and subjective: there’s no clear criteria for what counts as “better.” The second question is much more . It uses clearly defined terms and narrows its focus to a specific population.
It is generally not for academic research to answer broad normative questions. The second question is more specific, aiming to gain an understanding of possible solutions in order to make informed recommendations.
The first question is too simple: it can be answered with a simple yes or no. The second question is , requiring in-depth investigation and the development of an original argument.
The first question is too broad and not very . The second question identifies an underexplored aspect of the topic that requires investigation of various  to answer.
The first question is not enough: it tries to address two different (the quality of sexual health services and LGBT support services). Even though the two issues are related, it’s not clear how the research will bring them together. The second integrates the two problems into one focused, specific question.
The first question is too simple, asking for a straightforward fact that can be easily found online. The second is a more question that requires and detailed discussion to answer.
? dealt with the theme of racism through casting, staging, and allusion to contemporary events? The first question is not  — it would be very difficult to contribute anything new. The second question takes a specific angle to make an original argument, and has more relevance to current social concerns and debates.
The first question asks for a ready-made solution, and is not . The second question is a clearer comparative question, but note that it may not be practically . For a smaller research project or thesis, it could be narrowed down further to focus on the effectiveness of drunk driving laws in just one or two countries.

Note that the design of your research question can depend on what method you are pursuing. Here are a few options for qualitative, quantitative, and statistical research questions.

Type of research Example question
Qualitative research question
Quantitative research question
Statistical research question

Other interesting articles

If you want to know more about the research process , methodology , research bias , or statistics , make sure to check out some of our other articles with explanations and examples.

Methodology

  • Sampling methods
  • Simple random sampling
  • Stratified sampling
  • Cluster sampling
  • Likert scales
  • Reproducibility

 Statistics

  • Null hypothesis
  • Statistical power
  • Probability distribution
  • Effect size
  • Poisson distribution

Research bias

  • Optimism bias
  • Cognitive bias
  • Implicit bias
  • Hawthorne effect
  • Anchoring bias
  • Explicit bias

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